Biological activity of saturated diethers viz. 1-benzyloxy/phenoxy-8-alkoxy and 1-alkoxy-8-benzyloxy-3,7-dimethyl-1, 8-octanes (IIa-IIq) prepared from Geraniol, were studied on three mosquito species and the bug Dysdercus koenigii. These diethers exhibited oviposition deterrent and developmental inhibition activities of greater magnitudes than the compounds based on citronellol reported in Part I of this paper. Some of these new compounds inhibit development of mosquitoes at 0.05 ppm and deter oviposition at 0.05 per cent doses. Tests were extended to field simulated conditions in selected cases.
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Neotrop Entomol
January 2025
Institute of Agricultural Sciences, Federal Rural University of the Amazon - UFRA, Belém, PA, Brazil.
Brazil has 10.2 million hectares of reforestation, which account for 81% of the timber produced in the country. The order Hemiptera contains the main phytophagous species.
View Article and Find Full Text PDFNeotrop Entomol
January 2025
Research Center for Family Agriculture, Agricultural Research and Rural Extension Company of Santa Catarina (CEPAF/EPAGRI), Chapecó, Santa Catarina, Brazil.
To understand the interactions of entomopathogenic fungi with forage plants and their influence on associated herbivorous, we evaluated the influence of endophytic colonization with three isolates (CEPAF_ENT 25, CEPAF_ENT 27, and IBCB 425) of Metarhizium anisopliae on Cynodon dactylon, regarding the biological and behavioral aspects of Collaria scenica, an emerging sucking pest in pastoral systems in Brazil. The application of suspensions at the base of plant (drench) was effective in promoting endophytic colonization, especially in the roots, with emphasis on isolates CEPAF_ENT25 and CEPAF_ENT27. Despite the significant reduction in damage caused by C.
View Article and Find Full Text PDFMalar J
January 2025
Caribbean Centre for Research in Biosciences, Natural Products Institute, University of the West Indies, Kingston, Jamaica.
Background: Synergists reduce insecticide metabolism in mosquitoes by competing with insecticides for the active sites of metabolic enzymes, such as cytochrome P450s (CYPs). This increases the availability of the insecticide at its specific target site. The combination of both insecticides and synergists increases the toxicity of the mixture.
View Article and Find Full Text PDFJ Enzyme Inhib Med Chem
December 2025
Department of Biology Education, Teachers College and Institute for Phylogenomics and Evolution, Kyungpook National University, Daegu, Republic of Korea.
This study investigated the potential of the indirubin-3'-oxime (I3O) compound to mitigate temperature-induced male infertility in . Elevated temperatures significantly reduced egg-hatching rates, but I3O supplementation improved these rates, suggesting it can partially restore fertility under heat stress. Additionally, I3O was found to inhibit soluble epoxide hydrolase (sEH), an enzyme involved in the metabolism of epoxyeicosatrienoic acids, which are vital for reproductive health.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Hesperidin, a natural flavanone glycoside predominantly found in citrus fruits, has gained attention for its wide-ranging biological activities, including potential insecticidal properties. Culex pipiens, commonly known as the northern house mosquito, is a major vector of several human pathogens, such as the West Nile virus and filariasis, making it a key target in the fight against vector-borne diseases. In this study, we evaluated the larvicidal activity of Hesperidin against Culex pipiens larvae, assessing its potential as an alternative to chemical insecticides.
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