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Magnusiomyces capitatus is an environmental fungus found in soil, water, air, plants, and dairy products which may cause opportunistic infections in patients with haematological disorders resulting in high mortality rates. This series of the first reported cases in Ireland discusses investigation of two patients with underlying haematological disorders, hospitalised in the Irish National Adult Stem Cell Transplant Unit (NASCTU), who developed line-related fungaemias with M. capitatus within a three-month period.

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Toxoplasmosis, a parasitic disease, can cause fatal multi-organ failure in immunocompromised patients. The lack of specificity in the symptoms and the need to confirm a diagnosis of tachyzoites in fluids or tissues through microscopic examination leads to a delay in reaching a diagnosis. A 28-year-old woman with severe aplastic anemia received stem cell transplantation seven months ago, presented with fever.

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Article Synopsis
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder causing anemia and thrombosis due to a deficiency of specific membrane proteins, which may lead to severe neutropenia and a risk of neutropenic enterocolitis (NEC).
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Article Synopsis
  • * A 24-year-old woman with AA presented with chest pain and was found to have a thrombus in her coronary artery, leading to a heart attack and subsequent renal infarction, prompting further examinations and diagnoses.
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Bone marrow aplasia is a rare and serious hematologic disorder. Although benign, it is a hematologic disorder whose prognosis can be poor and whose spontaneous development can be fatal. Treatment is long, difficult and costly.

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