[RFLP-PCR technique for exclusion of carrier status of the mutated Rb gene].

Klin Oczna

Zakładu Genetyki i Patomorfologii Instytutu Patologii, Pomorskiej AM.

Published: June 1993

Molecular-genetic analysis of DNA by PCR-RFLP technique in a family with a case of unilateral retinoblastoma was performed. The carrier status of mutated Rb gene in a sister of proband was excluded on the basis of molecular analysis despite unsynonymous pedigree data.

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