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Indian J Pediatr
December 2024
Division of Endocrinology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Objectives: To present cases of rapid onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) and discuss management insights.
Methods: Case records of patients fulfilling the criteria for ROHHAD and presenting to the Pediatric Endocrinology Division of All India Institute of Medical Sciences, New Delhi, between July 2019 and June 2024 were reviewed for clinical features, treatments, and outcomes.
Results: Five patients (4 boys, 1 girl) presented at a median age of 4 y (range 3.
Brain Sci
October 2024
Bristol Royal Hospital for Children, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol BS2 8BJ, UK.
Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare syndrome presenting in early childhood associated with a high risk of mortality between 50 and 60%. It is characterised by rapid, early onset of obesity between 1.5-7 years, along with central hypoventilation and hypothalamic dysfunction, such as central hypothyroidism, hyperprolactinemia, disorders of sodium and water balance, growth hormone deficiency, adrenocortical insufficiency, or disorders of puberty and features of autonomic dysregulation.
View Article and Find Full Text PDFWomens Health Rep (New Rochelle)
July 2024
Department of Community Medicine and Behavioural Sciences, College of Medicine, Kuwait University, Kuwait.
Medicina (Kaunas)
August 2024
Department of Neurosurgery, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Adv Rheumatol
August 2024
University Hospital of Brasilia, Brasilia, Brazil.
Background: In the context of rheumatoid arthritis and its systemic inflammatory implications, there is an increasing interest in investigating the role of prolactin in the clinical and metabolic aspects of the disease. This study aimed to explore the potential links between serum prolactin levels, serum glucose levels, and the clinical manifestations of arthritis.
Methods: This exploratory, cross-sectional, observational study focused on women diagnosed with rheumatoid arthritis.
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