Background: The purpose of this report is to describe the body surface potential maps (BSPMs) during idiopathic ventricular tachycardia (VT) and to determine what differences exist between different idiopathic VT morphologies.
Methods And Results: We performed BSPMs during VT on 12 consecutive patients (3 women and 9 men; mean age, 42 +/- 13 years) presenting symptomatic idiopathic VT referred to our institution for electrophysiological study. Basal ECG, chest radiograph, and echocardiogram were normal in all patients. Clinical tachycardia showed left bundle branch block pattern (LBBB) in 9 patients, with sustained VT in 5 and nonsustained VT in 4, and right bundle branch block pattern (RBBB) in 3 with sustained VT. We found a unique pattern of BSPMs in each of the 9 patients during idiopathic LBBB VT configuration, whether sustained or nonsustained VT. This pattern appeared at the onset of the QRS and remained stable during the whole QRS complex. The area of minimal potential located in the upper anterior part of the torso was compatible with an origin of VT in the right ventricular outflow tract, as confirmed in 5 patients by successful radiofrequency ablation. We found an evolving pattern with two phases in each of the three RBBB VTs. The electrical axis during the initial part of the QRS could correspond to an endocardial-epicardial vector. The second phase, with a high voltage and area of minimal potential located in the inferior and anterior part of the torso, was compatible with a left ventricular apical origin that was confirmed by epicardial and endocardial mapping during cryosurgery in 1 patient. For all the VTs, the QRS isoarea maps showed the same pattern as the second phase of the QRS.
Conclusions: Two different BSPM patterns were found. All LBBB VTs had the same stable pattern corresponding to an infundibular origin. All RBBB VTs had an evolving pattern that stabilized in the second part of the QRS complex corresponding to an apical origin.
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http://dx.doi.org/10.1161/01.cir.91.7.2002 | DOI Listing |
Nature
January 2025
Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ, USA.
Evaporation or freezing of water-rich fluids with dilute concentrations of dissolved salts can produce brines, as observed in closed basins on Earth and detected by remote sensing on icy bodies in the outer Solar System. The mineralogical evolution of these brines is well understood in regard to terrestrial environments, but poorly constrained for extraterrestrial systems owing to a lack of direct sampling. Here we report the occurrence of salt minerals in samples of the asteroid (101955) Bennu returned by the OSIRIS-REx mission.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki-cho, Kita-gun, Takamatsu, 761-0793, Kagawa, Japan.
This study aims to evaluate the potential enhancement in implant classification performance achieved by incorporating artificially generated images of commercially available products into a deep learning process of dental implant classification using panoramic X-ray images. To supplement an existing dataset of 7,946 in vivo dental implant images, a three-dimensional scanner was employed to create implant surface models. Subsequently, implant surface models were used to generate two-dimensional X-ray images, which were compiled along with original images to create a comprehensive dataset.
View Article and Find Full Text PDFSci Adv
January 2025
Graduate School of Information Science and Technology, Hokkaido University, Sapporo 060-0814, Japan.
Integr Environ Assess Manag
January 2025
Faculty of Fine Arts, Design and Architecture Department of Landscape Architecture, Tekirdağ Namık Kemal University, Tekirdağ, Türkiye.
Wetlands provide necessary ecosystem services, such as climate regulation and contribution to biodiversity at global and local scales, and they face spatial changes due to natural and anthropogenic factors. The degradation of the characteristic structure signals potential severe threats to biodiversity. This study aimed to monitor the long-term spatial changes of the Göksu Delta, a critical Ramsar site, using remote sensing techniques.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
January 2025
Department of Dermatology, University of Tsukuba, Tsukuba, Japan.
Introduction: Patients with moderate-to-severe atopic dermatitis (AD), a body surface area (BSA) of ≤ 40%, and an itch numerical rating scale (NRS) score of ≥ 7 ("BARI itch dominant") have been characterized as an important group to consider for the oral janus kinase (JAK) 1/2 inhibitor baricitinib (BARI). Herein we aim to evaluate quality of life (QoL) and functioning outcomes in adult patients with BSA ≤ 40% and itch NRS ≥ 7 at baseline (BL) who received BARI 4 mg in the topical corticosteroid (TCS) combination trial BREEZE-AD7.
Materials: BREEZE-AD7 was a randomized, double-blind, placebo-controlled, parallel-group outpatient study involving adult patients with moderate-to-severe AD who received once-daily placebo or 2-mg or 4-mg BARI in combination with TCS for 16 weeks.
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