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A patient with a history of pelvic radiation therapy for seminoma presented with a prostatic tumor, which appeared predominantly of high signal intensity on T2-weighted magnetic resonance images; low-signal-intensity tissue also extended to the pelvic sidewall. At surgical pathology, the tumor was determined to be radiation-induced sarcoma of the prostate, and the extraprostatic tissue was postradiation fibrosis.
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http://dx.doi.org/10.1016/0899-7071(94)00017-7 | DOI Listing |
Oral Oncol
March 2025
Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address:
Purpose: This study aimed to investigate the ability of thyroid volumes after intensity-modulated radiotherapy (IMRT) to predict the incidence of radiation-induced hypothyroidism/primary hypothyroidism (HT)/(PHT) in nasopharyngeal carcinoma (NPC) patients.
Methods And Materials: 404 NPC patients were retrospectively enrolled from January 2015 to January 2019. Thyroid volumes were calculated based on magnetic resonance imaging.
Eur Radiol
March 2025
Department of Radiology, Xiangya Hospital of Central South University, Changsha, China.
Objectives: To evaluate the benefits of an automated deep learning-based tool (RTLI-DM) for early detection of radiation-induced temporal lobe injury (RTLI) on MRI.
Materials And Methods: A total of 396 RTLI and 3181 non-RTLI patients were retrospectively included from a cohort of 6483 NPC patients who underwent radiotherapy and MRI follow-ups at four hospitals from January 2010 to June 2021. We developed and validated an automated RTLI-DM using the initial abnormal MRI of RTLI patients and the final MRI of non-RTLI patients.
Cancer Med
March 2025
Department of Radiation Oncology, Tata Memorial Centre, Mumbai, India.
Introduction: Chlorophyllin (CHL) effectively decreases the side effects of radiotherapy (RT) by scavenging radiation-induced free radicals and reactive oxygen species in preclinical trials. This study aims to assess the efficacy of oral CHL for the treatment of brain radionecrosis in patients with diffuse glioma.
Methods: This is a phase 2 trial prospective, interventional study.
J Ethnopharmacol
February 2025
Clinical Pharmacy Center, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China; Zhejiang Provincial Clinical Research Center for malignant tumor, Hangzhou 310014, China; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou 310014, China. Electronic address:
Ethnopharmacological Relevance: Traditional Chinese medicine Botrychium ternatum (Thunb.) Sw, also known as Sceptridium ternatum (STE) has the efficacy of relieving cough and asthma, resolving phlegm, and clearing heat and toxicity. However, the effects and mechanisms of STE on RIPF have not been reported.
View Article and Find Full Text PDFEur J Surg Oncol
February 2025
Copenhagen University Hospital, Department of Plastic Surgery and Burns Treatment, Rigshospitalet, Copenhagen, Denmark; Copenhagen University, Department of Clinical Medicine, Copenhagen, Denmark.
Background: The prognostic impact of subclassifying tumors as primary and secondary cutaneous angiosarcoma (cAS) in terms of the risk of local recurrence, metastasis, disease-specific mortality, and overall survival has not been extensively investigated in previous studies. This study aimed to characterize the clinicopathological features and estimate the 2-, 5-, and 10-year rates of local recurrence, metastasis, disease-specific death, and overall survival for patients with primary and secondary cAS, and to propose a follow-up recommendation for these patients.
Methods: All Danish patients diagnosed with cAS between 2000 and 2023 were included.
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