The resin of Dracaena cochinchinensis has been used as the substitute for Chinese drug Xuejie (Sanguis Draconis) for 20 years in China. The pharmacological, toxicological and clinical studies have shown that the former is similar to the latter in effects, and can be used as a substitute for the latter. This paper deals with the resources, morphological and histological characters, chemical and physical analysis of Sanguis Lignum Dracaenae Cochinchinensis.
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Zhongguo Zhong Yao Za Zhi
July 2024
School of Life Sciences, Beijing University of Chinese Medicine Beijing 102488, China.
Clinical efficacy and mechanism of Qishen Yiqi Dripping Pills(QSYQ) have been well researched, but the compatibility mechanism underlying its therapeutic effect still requires further analysis. This study aims to explore the compatibility mechanism of QSYQ in treating myocardial ischemia. UPLC-Q-Exactive Orbitrap-MS technique was used to obtain the absorbed blood components of QSYQ.
View Article and Find Full Text PDFMolecules
July 2024
Department of Pharmacy, Inner Mongolia Medical University, Hohhot 010110, China.
Objective: To elucidate the chemical profile of Xanthocerais lignum's extracts of different polarities and their impact on rheumatoid arthritis (RA), we identified anti-RA markers and predicted their action mechanisms.
Methods: A collagen-induced arthritis rat model was established, and UPLC-Q-Exactive Orbitrap MS technology was employed to analyze and identify the chemical constituents within the alcohol extract of Xanthocerais lignum and its various extraction fractions, as well as their translocation into the bloodstream. Serum spectrum-effect correlation analysis was utilized to elucidate the pharmacodynamic material basis of Xanthocerais lignum against RA and to screen for Q-Markers.
Zhongguo Zhong Yao Za Zhi
December 2022
School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Dalbergia cochinchinensis(DC) is chemically similar to the valuable and scarce Chinese herb Dalbergiae Odoriferae Lignum, and both of them belong to the Dalbergia Leguminosae. DC is used for treating cardiovascular diseases and cancer. However, its potent active ingredient groups and molecular mechanisms in anti-myocardial ischemia are not fully clarified.
View Article and Find Full Text PDFMol Med Rep
July 2021
Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, P.R. China.
Guan Xin Dan Shen formulation (GXDSF) is a widely used treatment for the management of coronary heart disease in China and is composed of three primary components: , Radix et Rhizoma and Radix et Rhizoma. However, the potential use of GXDSF for the management of diabetic cardiomyopathy (DCM) has not been previously assessed. The present study aimed to assess the effects of GXDSF on DCM, as well as the underlying mechanism.
View Article and Find Full Text PDFCurr Drug Metab
January 2022
The Second Clinical Medical College, and Guangdong Provincial Key Laboratory of Chinese Medicine for Prevention and Treatment of Refractory Chronic Diseases, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Background: Caesalpinia sappan L. is a traditional medicinal plant that is used to promote blood circulation and treat stroke in China. Protosappanin B (PTB) is a unique homoisoflavone compound isolated from Sappan Lignum (the heartwood of Caesalpinia sappan L).
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