[Systemic emulsions. 2. Use of different methods of formulation: the effect of essential oils of thyme on stability].

J Pharm Belg

Faculté de Pharmacie, Laboratoire de Technique Pharmaceutique Industrielle, Montpellier.

Published: April 1995

As part of an ongoing investigation on emulsifying techniques, we studied the influence of different essential oils from Thymus vulgaris on emulsion stability. All four chimiotypes tested (geraniol, linalol, carvacrol, and thymol) caused a marked decrease in stability. This instability cannot be explained by a change in the hydrophilic lipophilic balance since the HLBc of the new oil phase (essential oil + paraffine oil) was not significantly different from that of paraffine alone.

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