We report the clinical characteristics of the developmental right-hemisphere syndrome (DRHS), a nonverbal learning disability, in 20 children (9 girls and 11 boys; mean age = 9.5 years) who also manifested attention-deficit/hyperactivity disorder (ADHD), severe graphomotor problems, and marked slowness of performance. Diagnostic criteria for this study included (a) emotional and interpersonal difficulties; (b) paralinguistic communication problems; (c) impaired visuospatial skills, verbal IQ > performance IQ, and verbal IQ > or = 85; and either (d) dyscalculia or (e) neurological signs on the left side of the body. In this group, verbal IQ was significantly higher than performance IQ (106.6 +/- 13.0 vs. 85.1 +/- 13.1, respectively, p < .01). Arithmetic was the lowest score among the verbal subtests (7.8 +/- 3.5, p < .01) and Geometrical Design was the lowest score among the performance subtests (5.8 +/- 1.7). Thirteen children had soft neurological signs on the left side of the body. ADHD was seen in all 20 children, marked slowness of performance in 16, and severe graphomotor problems in 18. The latter two features have not been previously described as part of DRHS.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Preservation of Bilateral Corticospinal Projections from Injured Hemisphere After Perinatal Stroke.
Brain Sci
January 2025
Waisman Center, University of Wisconsin-Madison, Madison, WI 53706, USA.
Background: Perinatal brain injury is a leading cause of developmental disabilities, including cerebral palsy. However, further work is needed to understand early brain development in the presence of brain injury. In this case report, we examine the longitudinal neuromotor development of a term infant following a significant loss of right-hemispheric brain tissue due to a unilateral ischemic stroke.
View Article and Find Full Text PDFLateralization of Neural Speech Discrimination at Birth Is a Predictor for Later Language Development.
Dev Sci
March 2025
Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria.
Newborns are able to neurally discriminate between speech and nonspeech right after birth. To date it remains unknown whether this early speech discrimination and the underlying neural language network is associated with later language development. Preterm-born children are an interesting cohort to investigate this relationship, as previous studies have shown that preterm-born neonates exhibit alterations of speech processing and have a greater risk of later language deficits.
View Article and Find Full Text PDFResponse strength and latencies of auditory steady-state responses from age six.
Int J Audiol
January 2025
Department of Neurosciences, Research Group ExpORL, KU Leuven, Leuven, Belgium.
Objective: Auditory-steady state responses (ASSRs) to stimuli modulated by different frequencies may differ between children and adults. These differences in response characteristics or latency may reflect developmental changes. This study investigates age-related differences in response strength, latencies, and hemispheric laterality indices of ASSRs for different modulation frequencies.
View Article and Find Full Text PDFAbnormalities in cerebellar subregions' volume and cerebellocerebral structural covariance in autism spectrum disorder.
Autism Res
January 2025
Department of Anatomy and Neurobiology, Research Center for Sectional and Imaging Anatomy, Shandong Provincial Key Laboratory of Mental Disorder, Shandong Key Laboratory of Digital Human and Clinical Anatomy, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
The cerebellum plays a crucial role in functions, including sensory-motor coordination, cognition, and emotional processing. Compared to the neocortex, the human cerebellum exhibits a protracted developmental trajectory. This delayed developmental timeline may lead to increased sensitivity of the cerebellum to external influences, potentially extending the vulnerability period for neurological disorders.
View Article and Find Full Text PDFIs an earlier onset of focal epilepsy associated with atypical language lateralization? A systematic review, meta-analysis and new data.
medRxiv
November 2024
Developmental Neurosciences Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK.
Article Synopsis
- Right and bilateral language representation in focal epilepsy may be influenced by seizure activity and lesions in the left hemisphere, with research suggesting that earlier seizure onset could lead to atypical language lateralization due to childhood brain plasticity.
- A meta-analysis examined the link between age at seizure onset and language lateralization using fMRI, finding a small but significant correlation (r=0.1, p=.005) between earlier onset and rightward lateralization across various samples.
- The study concluded that while there is a slight association consistent with theories of declining language plasticity, this relationship is subtle and not a reliable indicator of atypical language lateralization for individual patients.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!