We describe a previously healthy 69-year-old man presenting with osteomyelitis of the humerus due to the zygomycete Apophysomyces elegans. The infection was acquired in Aruba, The Netherlands Antilles. The skin provided the most likely portal of entry, although there was no history of a traumatic inoculation. The patient had no history of diabetes, and no underlying immune defects were found. Despite treatment with 7.9 g of amphotericin B, an interthoracoscapular amputation proved necessary to curtail the rapid spread of the fungus in this immunocompetent host.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC264235 | PMC |
| http://dx.doi.org/10.1128/jcm.32.12.3078-3081.1994 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of a monoclonal antibody and a lateral-flow device for the rapid detection of a Mucorales-specific biomarker.
Front Cell Infect Microbiol
December 2023
Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom.
Article Synopsis
- Current diagnosis methods are slow and non-specific, lacking rapid tests for identifying specific Mucorales infections.
- A new IgG2b monoclonal antibody (TG11) has been developed that detects specific polysaccharide antigens, enabling a quick 30-minute test for mucoromycosis in human serum and bronchoalveolar lavage samples.
Rise of mucormycosis during the COVID-19 pandemic and the challenges faced.
Curr Med Mycol
March 2023
Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Mucormycosis (previously called zygomycosis) is a diverse group of increasingly recognized and frequently fatal mycotic diseases caused by members of the class zygomycetes. Mucormycosis is around 80 times more common in India, compared to other developed countries, with a frequency of 0.14 cases per 1,000 population.
View Article and Find Full Text PDFMolecular epidemiology of zygomycosis and their related factors in tertiary referral centers in southern Iran.
J Infect Dev Ctries
December 2020
Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction: For the best management of the zygomycosis in immunocompromised patients, the present study aims to detect and identify the etiologic agents by DNA sequencing method and their related factors in clinical samples of patients.
Methodology: Clinical samples from 1,058 patients admitted in 11 university hospitals in Shiraz, Southern Iran were collected between July 2015 and July 2018. All samples (bronchoalveolar lavage, sputum, blood, tissue) were examined by routine microscopic and culture tests for zygomycetes.
Necrotizing fasciitis caused by in an immunocompetent patient.
Med Mycol Case Rep
June 2018
Clínica Erasmo, Valledupar, Colombia.
Mucormycosis caused by Apophysomyces variabilis is rarely reported in humans. A case of A. variabilis infection in an immunocompetent men after friction burns in a car accident is described.
View Article and Find Full Text PDFSkull Base Osteomyelitis Caused by an Elegant Fungus.
J Assoc Physicians India
February 2016
Assistant Professor, Dept. of ENT.
Malignant otitIs externa (skull base osteomyelitis) is predominantly caused by bacteria while fungal etiology is rare. We report a middle aged diabetic gentleman who succumbed to invasive skull base infection due to Apophysomyces elegans a fungus belonging to Zygomycetes which causes only skin and soft tissue infections. Mortality and invasive infections due to this genus is rarely reported, especially in the ear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!