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Histological Features of Delayed Foreign Body Granuloma With Epithelioid Histiocyte Aggregation and Eosinophilic Reaction due to Hyaluronic Acid Injection.
Case Rep Dent
December 2024
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan.
Dermal fillers such as hyaluronic acid (HA) have been widely used in recent years as a less surgically invasive cosmetic treatment. Although delayed foreign body granuloma may occur as a rare adverse reaction after the procedure, detailed histological reports are still limited. When occurring on the buccal mucosa of the oral cavity, the histopathology may resemble some lesions of minor salivary gland origin due to the material properties of HA.
View Article and Find Full Text PDFPathology of rheumatoid meningitis: A report of 5 cases highlighting the importance of clinical correlation.
Ann Diagn Pathol
February 2025
Department of Pathology, University of Colorado Health Science Center, Anschutz Medical Campus, Aurora, CO, USA; Department of Neurosurgery, University of Colorado Health Science Center, Anschutz Medical Campus, Aurora, CO, USA; Department of Neurology, University of Colorado Health Science Center, Anschutz Medical Campus, Aurora, CO, USA.
Rheumatoid meningitis (RM) presents with sufficiently wide-ranging, but non-specific, symptoms and neuroimaging features of pachy- and/or leptomeningeal thickening that it may be indistinguishable from subacute infectious meningitis. RA diagnosis variably antedates RM and serological confirmation by rheumatoid factor and anti-citrullinated peptide antibodies may not be present preoperatively. Thus, meningeal biopsy may be undertaken.
View Article and Find Full Text PDFA Rare Cause of Pancytopenia From Lepromatous Leprosy Diagnosed in Bone Marrow Aspiration: A Bolt From the Blue.
Cureus
September 2024
Department of Pathology, SRM Medical College Hospital and Research Center, SRM Institute of Science and Technology (SRMIST), Chengalpattu, IND.
Article Synopsis
- Hansen's disease, or leprosy, primarily affects individuals with a weakened T-cell immune response, leading to symptoms like red to brown nodules on the skin, particularly on the face and ear areas.
- A unique case involved a 40-year-old man who presented with fever and altered mental status, which is atypical for leprosy.
- Diagnosis was made through bone marrow aspiration, which is uncommon since leprosy is usually confirmed via skin biopsy, and instances of lepra bacilli in bone marrow are rarely documented.
Gaucher-like crystal-storing histiocytosis associated with kappa chain myeloma: A case report with next generation sequencing study.
Pathol Res Pract
November 2024
Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Article Synopsis
- * The case study illustrates a patient with kappa chain myeloma who exhibited Gaucher-like crystal-storing histiocytosis in bone marrow, identified through various methods including biopsy and next generation sequencing (NGS).
- * Findings indicated the presence of distinct rhomboid crystals and several genetic mutations linked to poorer survival rates in myeloma patients, suggesting that pathologists should consider crystal-storing histiocytosis when identifying such crystals in bone marrow.
Supranuclear Palsy as an Initial Presentation of the Adult-Onset Niemann-Pick Type C.
Neurol Int
May 2024
Department of Neurology, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
(1) Background: Niemann-Pick type C1 (NP-C1) is a lysosomal storage disorder that results in the defective trafficking of cholesterol and other cellular lipids in the endosomal-lysosomal pathway. This rare autosomal recessive disorder presents in three forms based on the age of onset. The adult form presents in patients greater than 15 years of age but is rarely seen after the age of 30.
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