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Androgen receptor overexpression by immunohistochemistry in malignant salivary gland tumors in Tanzania.
BMC Cancer
January 2025
Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Background: Malignant salivary gland tumors (SGTs) present diagnostic challenges and limited treatment options. This study aims to determine the proportion of malignant SGTs overexpressing the androgen receptor (AR) by immunohistochemistry (IHC) and its association to age, sex, anatomical site, histopathological subtype and grade which may inform customized treatment approaches.
Methodology: This was a retrospective cross-sectional analytical study of archived paraffin embedded tissue blocks of malignant SGTs diagnosed at MNH Central Pathology Laboratory (CPL) from January 2019 to December 2022.
From asthma exacerbation to pulmonary mucoepidermoid carcinoma: A rare case report.
Int J Surg Case Rep
January 2025
Department of Pathology, Al-Istishari Hospital, Ramallah, Palestine.
Introduction And Importance: Pulmonary mucoepidermoid carcinoma (PMEC) is a rare lung tumor, accounting 0.1-0.2 % of lung malignancies, commonly affecting adults under 50.
View Article and Find Full Text PDF[Resected Pulmonary Mucoepidermoid Carcinoma Containing High-grade Lesions in a Young Adult:Report of a Case].
Kyobu Geka
November 2024
Department of Thoracic Surgery, Shimane Prefectural Central Hospital, Izumo, Japan.
A 20-year-old female underwent a health checkup that revealed an abnormal shadow in the left upper lung field on a chest radiograph. A further examination with chest computed tomography( CT) showed a 25 mm solid tumor in the center of B1+2 in the left upper lobe. A biopsy of the tumor obstructing the left B1+2 was performed during bronchoscopy, and a pathological study diagnosed it as mucoepidermoid carcinoma of the lung.
View Article and Find Full Text PDFSclerosing Mucoepidermoid Carcinoma With Eosinophilia of the Thyroid: A Rare Case From Georgia and a Comprehensive Literature Review.
Cureus
October 2024
Department of Pathology and Forensic Medicine, Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, GEO.
Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a rare thyroid malignancy typically linked to chronic lymphocytic thyroiditis. We present the first documented case of SMECE in Georgia, involving a 41-year-old woman with Hashimoto's thyroiditis. A 16 mm hypoechoic thyroid nodule was detected on routine ultrasound, and fine needle aspiration categorized it as Bethesda V.
View Article and Find Full Text PDFTreatment Outcomes and Patterns of Disease Recurrence of Patients with Carcinoma of the Buccal Mucosa.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Radiotherapy, M L N Medical College, Prayagraj, Uttar Pradesh India.
Article Synopsis
- The study focuses on treating locally advanced buccal mucosa cancer, primarily through surgery and postoperative radiotherapy with specific chemotherapy regimens, including Cisplatin and 5-Fluorouracil.
- It evaluates the effectiveness of de-escalated treatment using ipsilateral face radiotherapy, which targets only the affected side of the face to improve functions like chewing and mitigate side effects.
- A total of 54 patients were reviewed retrospectively, revealing treatment patterns and outcomes, including indications for radiation based on tumor margins and lymph node involvement, along with one patient's alternative treatment approach leading to poor outcomes.
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