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Does Ankyloglossia Surgery Promote Normal Facial Development? A Systematic Review.
J Clin Med
December 2024
The Department of Dentofacial Orthopaedics and Orthodontic, Wroclaw Medical University, 50-425 Wroclaw, Poland.
Ankyloglossia is a congenital, abnormally short, thickened, or tight lingual frenulum that restricts tongue mobility, which may impair the development of the lower face morphology, namely the occlusion and skeleton. The aim of this study was to evaluate whether and how the lingual frenotomy benefits the occlusion and lower face skeleton development. The authors, independently and in duplication, performed searches of PubMed, Cochrane Library, Medline, Web of Science, and Embase, introducing the following keywords: tongue tie, ankyloglossia, and short lingual frenum/frenulum, combined with malocclusion, lower face skeleton, and hyoid bone.
View Article and Find Full Text PDFPTN secreted by cardiac fibroblasts promotes myocardial fibrosis and inflammation of pressure overload-induced hypertrophic cardiomyopathy through the PTN-SDC4 pathway.
Life Sci
January 2025
Basic Medical Research Center, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address:
Aims: Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular hypertrophy (LVH) with key pathologic processes including myocardial necrosis, fibrosis, inflammation, and hypertrophy, which are involved in heart failure (HF), stroke, and even sudden death. Our aim was to explore the communication network among various cells in the heart of transverse aortic constriction (TAC) surgery induced HCM mice.
Materials And Methods: Single-cell RNA-seq data of GSE137167 was downloaded from the Gene Expression Omnibus (GEO) database.
Advances in the Treatment of Neonatal Coarctation of the Aorta.
Pediatrics
January 2025
Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.
Coarctation of the aorta (CoA) is a potentially life-threatening congenital and obstructive anomaly of the distal aortic arch. After constriction of the ductus arteriosus, neonates may develop critical CoA in the isthmus area and present with severe left ventricular dysfunction or even cardiac failure. Low cardiac output and abdominal hypoperfusion (distal to the coarctation) may lead to metabolic derangements and clinical deterioration.
View Article and Find Full Text PDFImportance: The diagnosis of congenital auricular deformity often relies on the clinical experience of clinicians, leading to a high incidence of misdiagnosis and missed diagnosis due to the lack of quantitative diagnostic criteria.
Objective: To characterize auricle morphology in newborns from southern China and explore the underlying etiology of congenital auricle deformity.
Methods: A total of 636 neonates (1272 ears) with less than seven days old were included.
Constrictive pericarditis following epicardial pacemaker implant: a diagnostic dilemma.
Cardiol Young
December 2024
Dept of Paediatric Cardiac Surgery, NH SRCC Children's Hospital, Mumbai, India.
Constrictive pericarditis is a rare complication after cardiac surgery. It is mostly seen in adults. We report a case of constrictive pericarditis in a 3-year-old child with right ventricular dysfunction after permanent pacemaker implantation during infancy for congenital complete heart block.
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