Study Objective: To develop an automatic mechanical device capable of performing active compression-decompression (ACD) CPR in laboratory animals.
Design: A swine model was used to study standard and ACD CPR. One-minute periods of standard mechanical chest compressions were alternated with mechanical ACD CPR.
Setting: University hospital laboratory.
Interventions: A commercially available device that provided standard chest compressions only was modified to deliver ACD CPR.
Results: The absolute difference in intrapleural pressure and tidal volume almost doubled during ACD CPR compared with that with standard CPR.
Conclusion: The presence of a greater negative change in intrapleural pressure confirmed that active decompression of the chest had occurred and that the device was capable of performing ACD CPR. The device provides consistent rate, depth, force, and duty cycle.
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http://dx.doi.org/10.1016/s0196-0644(95)70299-7 | DOI Listing |
Resuscitation
November 2024
Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000, Grenoble, France; Clinical Epidemiology Unit, University Hospital of Grenoble Alpes, Grenoble, France.
Resuscitation
September 2024
Department of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA. Electronic address:
Background: The combination of active compression-decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) and controlled head-up positioning (AHUP-CPR) is associated with improved outcomes compared with conventional CPR (C-CPR). This study focused on the role of active decompression (AD) during AHUP-CPR.
Methods: Farm pigs (n = 10, ∼40 kg) were anesthetized, intubated and ventilated.
Despite low out of hospital cardiac arrest (OOHCA) survival rates within the UK, animal studies hint at improved cerebral blood flow via a bundled neuroprotective CPR approach. The CABARET study introduces three key devices: the Head Up Position (HUP), Active Compression/Decompression (ACD) CPR, and the Impedance Threshold Device (ITD). A survey involving 27 UK pre-hospital critical care services indicated none are using these interventions widely, either alone or bundled.
View Article and Find Full Text PDFCureus
April 2023
Emergency Medicine, Lakeside Medical Center, Belle Glade, USA.
The study aims to assess cardiopulmonary resuscitation (CPR) outcomes in cardiac arrest patients when using CPR augmentation devices, such as the ZOLL ResQCPR system (Chelmsford, MA) or its components ResQPUMP and ResQPOD, which are manual active compression-decompression (ACD) device and impedance threshold device (ITD), respectively. The analysis included a Google Scholar-based literature review that took place between January 2015 and March 2023 and included recent publications with PubMed IDs or widely cited articles to assess the effectiveness of the ResQPUMP and ResQPOD or similar devices. This review also includes studies quoted by ZOLL, but those were not considered in our conclusion since the authors were employed by ZOLL.
View Article and Find Full Text PDFResuscitation
April 2023
Anesthesiology, TVHS VA Medical Center, Nashville, TN, USA; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA. Electronic address:
Aim: Increasing venous return during cardiopulmonary resuscitation (CPR) has been shown to improve hemodynamics during CPR and outcomes following cardiac arrest (CA). We hypothesized that a high central venous pressure amplitude (CVP-A), the difference between the maximum and minimum central venous pressure during chest compressions, could serve as a robust predictor of return of spontaneous circulation (ROSC) in addition to traditional measurements of coronary perfusion pressure (CPP) and end-tidal CO (etCO) in a porcine model of CA.
Methods: After 10 min of ventricular fibrillation, 9 anesthetized and intubated female pigs received mechanical chest compressions with active compression/decompression (ACD) and an impedance threshold device (ITD).
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