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A network meta-analysis of therapies for hyperphosphatemia in CKD based on randomized trials.
Sci Rep
January 2025
College of Traditional Chinese Medicine, Shandong Second Medical University, Weifang, China.
To update the efficacy and safety of different drugs for the treatment of patients with hyperphosphatemia in chronic kidney disease, we conducted a network meta-analysis of 22 therapies for the treatment of uncontrolled hyperphosphatemia in patients with chronic kidney disease (CKD). All randomized controlled trials on hyperphosphatemia published from January 2013 to November 2023 were searched from CNKI, VIP database, Wanfang database, PubMed, Scopus, and Cochrane databases. Meta-analysis was used to evaluate the serum phosphorus, calcium levels, total effective rate and adverse events of patients with chronic kidney disease (CKD).
View Article and Find Full Text PDFHematological and biochemical parameters in the blood of working Belgian Shepherd dogs: An age-related study.
Open Vet J
November 2024
Department for Clinical Sciences, University of Sarajevo-Veterinary Faculty, Sarajevo, Bosnia and Herzegovina.
Background: Age-related changes in physiological parameters are crucial in understanding the health and performance of working dogs, particularly those in demanding roles such as military and law enforcement. However, limited research exists on how aging affects the hematological and biochemical health of these dogs.
Aim: This study aims to characterize age-related variations in hematological and biochemical parameters in working Belgian Shepherd dogs to provide insights that could inform health management strategies for these animals.
Article Synopsis
- Diabetic neuropathy is a common complication of diabetes that often leads to conditions like Charcot foot, characterized by local osteoporosis and vascular calcification in the lower extremities.
- Many patients with Charcot foot experience accelerated bone metabolism and imbalances in calcium and phosphorus levels, impacting their overall bone health.
- The review emphasizes the importance of timely diagnosis and treatment of vitamin D and mineral imbalances to manage complications in diabetes patients effectively, particularly through MRI for early detection of Charcot's foot.
Unravelling the Genetic Architecture of Serum Biochemical Indicators in Sheep.
Genes (Basel)
July 2024
Faculty of Agriculture, Department of Animal Science, Erciyes University, Kayseri 38039, Türkiye.
Serum biochemical indicators serve as vital proxies that reflect the physiological state and functions of different organs. The genetic parameters and molecular mechanisms underlying serum biochemical indicators of sheep () have not been well understood. Therefore, the aim of the present study was to identify the genetic architecture and genomic loci underlying ten serum biochemical indicators in sheep, including alanine transaminase, aspartate transferase, lactate dehydrogenase, cholesterol, glucose, phosphorus, calcium, creatinine, urea and total protein levels.
View Article and Find Full Text PDFEffect of dietary calcium source, exogenous phytase, and formic acid on inositol phosphate degradation, mineral and amino acid digestibility, and microbiota in growing pigs.
J Anim Sci
January 2024
Institute of Animal Science, University of Hohenheim, Stuttgart, Germany.
The choice of the calcium (Ca) source in pig diets and the addition of formic acid may affect the gastrointestinal inositol phosphate (InsP) degradation and thereby, phosphorus (P) digestibility in pigs. This study assessed the effects of different Ca sources (Ca carbonate, Ca formate), exogenous phytase, and chemical acidification on InsP degradation, nutrient digestion and retention, blood metabolites, and microbiota composition in growing pigs. In a randomized design, 8 ileal-cannulated barrows (24 kg initial BW) were fed 5 diets containing Ca formate or Ca carbonate as the only mineral Ca addition, with or without 1,500 FTU/kg of an exogenous hybrid 6-phytase.
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