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Carrel, Abraham Flexner, and Osler: selected World War I correspondence.
Proc (Bayl Univ Med Cent)
January 2025
Grenoble Alpes Faculty of Medicine, La Tronche, France (alumnus).
The relationship between Alexis Carrel, who received the Nobel Prize in Physiology or Medicine in 1912, and Simon Flexner, director of the Rockefeller Institute for Medical Research, is well documented. However, Carrel's collaboration with Abraham Flexner, a key figure in US medical reform, is less widely recognized, and it seems there are no previous mentions of a connection with William Osler. This historical vignette offers insights into the interactions among these three figures during World War I.
View Article and Find Full Text PDFA Brief History of Cell Culture: From Harrison to Organs-on-a-Chip.
Cells
December 2024
Department of Genetic, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14040-904, Brazil.
This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux's seminal experiments in the 1880s, followed by the pioneering efforts of Ross Granville Harrison, who initiated groundbreaking experiments that fundamentally shaped the landscape of cell culture in the early 20th century. Carrel's influential contributions, notably the immortalization of chicken heart cells, have marked a significant advancement in cell culture techniques.
View Article and Find Full Text PDFASO Author Reflections: Should We Resect the "Unresectable"? Since Alexis Carrel and Joseph G. Fortner, Almost 120 Years of (Pancreatic) Vascular Surgery in New York.
Ann Surg Oncol
April 2025
Division of Hepatobiliary and Pancreatic Surgery, NYU Langone Health, NYU Grossman School of Medicine, New York, NY, USA.
An Unexpected Partnership: Alexis Carrel, Charles Lindbergh, and Normothermic Machine Perfusion.
ASAIO J
October 2024
From the Division of Cardiac Surgery, Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio.
Organ transplantation is a triumph of modern medicine which represents a culmination of science and imagination, saving thousands of lives a year. However, transplantation is severely limited by suitable donor allografts. To expand the donor pool and make transplantation achievable for all, normothermic machine perfusion (NMP) is being employed more frequently.
View Article and Find Full Text PDFStatement on the Lancet Commission on Medicine, Nazism, and the Holocaust.
Lancet
November 2023
Center for Bioethics and Humanities, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
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