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Giant Duodenal Brunneroma: Report of a Rare Case and Review of the Literature.
Am J Case Rep
December 2024
Department of Visceral Surgery, Hospital of the Canton of St. Gallen, St. Gallen, Switzerland.
BACKGROUND Brunneromas are among the rarest benign tumors of the upper gastrointestinal tract. They arise from the Brunner's glands and patients have a good prognosis if treated timely and radically. Because symptoms are rare, their diagnosis can be challenging, especially regarding the smaller ones.
View Article and Find Full Text PDFBackground: Pyloric gland adenoma (PGA) is a distinct subtype of duodenal adenoma. PGA has been increasingly recognized as a histologically and molecularly distinct entity; however, its endoscopic features have not been precisely described. This study aims to investigate the endoscopic characteristics of duodenal PGA, including the association of their putative precursors, Brunner's gland hyperplasia (BGH), and gastric epithelial heterotopia/metaplasia (GEM/H).
View Article and Find Full Text PDFSingle-cell integration reveals metaplasia in inflammatory gut diseases.
Nature
November 2024
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and barrier immunity. Advances in genomics and a surge in gastrointestinal diseases has fuelled efforts to catalogue cells constituting gastrointestinal tissues in health and disease. Here we present systematic integration of 25 single-cell RNA sequencing datasets spanning the entire healthy gastrointestinal tract in development and in adulthood.
View Article and Find Full Text PDFDuodenal Brunner's gland hamartoma resected using laparoscopic and endoscopic cooperative surgery: A case report.
Int J Surg Case Rep
December 2024
Department of Surgery and Science, Kyushu University, Fukuoka, Japan. Electronic address:
Introduction And Importance: Brunner's gland hamartoma is a rare benign duodenal tumor. Resection is recommended for large or symptomatic lesions, but conventional pancreaticoduodenectomy and other procedures can be overly invasive for the lesion. We report a case of Brunner's gland hamartoma resected using laparoscopic and endoscopic cooperative surgery (LECS).
View Article and Find Full Text PDFA case of duodenal adenocarcinoma with a gastric phenotype demonstrating a rapidly progressive course.
Intern Med
November 2024
Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.
We herein report a rare case of duodenal adenocarcinoma with a rapidly progressive course. Esophagogastroduodenoscopy revealed Brunner's gland hyperplasia in the bulbs of the duodenum three years prior to this presentation. Two years earlier, gastric foveolar metaplasia had been observed in the bulbs.
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