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Equitable artificial intelligence for glaucoma screening with fair identity normalization.
NPJ Digit Med
January 2025
Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Glaucoma is the leading cause of irreversible blindness globally. Research indicates a disproportionate impact of glaucoma on racial and ethnic minorities. Existing deep learning models for glaucoma detection might not achieve equitable performance across diverse identity groups.
View Article and Find Full Text PDFVisual impairment prevention by early detection of diabetic retinopathy based on stacked auto-encoder.
Sci Rep
January 2025
Department of Robotics, Hanyang University, Ansan, 15588, Republic of Korea.
Diabetic retinopathy (DR) presents a significant concern among diabetic patients, often leading to vision impairment or blindness if left untreated. Traditional diagnosis methods are prone to human error, necessitating accurate alternatives. While various computer-aided systems have been developed to assist in DR detection, there remains a need for accurate and efficient methods to classify its stages.
View Article and Find Full Text PDFInsights into parental perspectives: Children's eye care in Saudi Arabia.
Heliyon
January 2025
King Faisal University, Department of Surgery, Ophthalmology Unit, Saudi Arabia.
Purpose: Despite the concerning growth in the number of children with preventable or treatable causes of blindness, parents and/or children often do not notice many eye problems due to the lack of adequate knowledge about them. Considering the lack of updated relevant literature on this topic, this study aimed to gain insights into parental perspectives regarding children's eye health and the barriers that prevent them from promptly addressing these issues.
Methods: A cross-sectional online survey was randomly distributed to Saudi parents of children aged 0-18 years from February 2022 to April 2022.
DNA methylation of long noncoding RNA cytochrome B in diabetic retinopathy.
Noncoding RNA Res
April 2025
Kresge Eye Institute, Wayne State University, Detroit, MI, USA.
Diabetic retinopathy, a microvascular complication of diabetes, is the leading cause of blindness in adults, but the molecular mechanism of its development remains unclear. Retinal mitochondrial DNA is damaged and hypermethylated, and mtDNA-encoded genes are downregulated. Expression of a long noncoding RNA (larger than 200 nucleotides, which does not translate into proteins), encoded by mtDNA, cytochrome B (Lnc), is also downregulated.
View Article and Find Full Text PDFRituximab (monoclonal anti-CD20 antibody) induced posterior reversible encephalopathy syndrome (PRES): A case report and literature review.
Radiol Case Rep
March 2025
Department of Radio-Diagnosis, Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai, Tamil Nadu 602105, India.
Posterior reversible encephalopathy syndrome (PRES) is an uncommon neurological condition characterized by reversible subcortical vasogenic edema that primarily affects the posterior areas of the brain. Subcortical vasogenic edema resulting from endothelial injury and hypertension is the pathogenesis. Here, we present a 23-year-old female patient with systemic lupus erythematosus (SLE) and lupus nephritis who developed PRES following Rituximab (a monoclonal anti-CD-20 antibody) administration.
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