The aims of this study were to determine the prevalence of hypertension (systolic > or = 140 and/or diastolic > or = 90 mmHg) and its subtypes such as borderline isolated systolic hypertension (systolic > or = 140, diastolic < 90 mmHg), definite isolated systolic hypertension (systolic > or = 160, diastolic < 90 mmHg), isolated diastolic hypertension (systolic < 160, diastolic > or = 90 mmHg) and definite hypertension (systolic > or = 160 and diastolic > or = 90 mmHg or hypertensives on treatment) in a rural population of a developing country. We have conducted a total community cross-sectional survey in a rural population of western India. 3148 persons (1982 males and 1166 females), aged > or = 20 years were examined in a cluster of three villages in Rajasthan. These were grouped into various subtypes of hypertension according to the US Fifth Joint National Committee and Framingham Study guidelines. The overall prevalence of hypertension and its subtypes was 24% in males and 17% in females. There was an age related increase in the prevalence of hypertension in both males and females. Only 7% males and 8% females were aware of their high BP. On subclassification of hypertensives it was seen that in males 12% had borderline isolated systolic hypertension, 2% had definite isolated systolic hypertension, 70% had isolated diastolic hypertension and 16% had definite hypertension. In females 18% had borderline isolated systolic hypertension, 2% had definite isolated systolic hypertension, 53% had isolated diastolic hypertension and 17% had definite hypertension.(ABSTRACT TRUNCATED AT 250 WORDS)
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Indian Heart J
January 2025
Department of Community Medicine, Dr. S. N. Medical College, Jodhpur, India.
Angiotensin Receptor Neprilysin Inhibitor (ARNI) has not shown to be promising in Heart failure with preserved LVEF. Role of ARNI in Right ventricular systolic dysfunction with preserved LVEF needs to be evaluated. We took 50 patients with isolated RV systolic dysfunction and divided them into two groups of 25 patients each- Conventional treatment and ARNI in addition to conventional treatment.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
School of Public Health, University of Haifa, Haifa, Israel.
Background: Increasing life expectancy has led to a rise in nursing home admissions, a context in which older adults often experience chronic physical and mental health conditions, chronic pain, and reduced well-being. Nonpharmacological approaches are especially important for managing older adults' chronic pain, mental health conditions (such as anxiety and depression), and overall well-being, including sensory stimulation (SS) and therapist support (TS). However, the combined effects of SS and TS have not been investigated.
View Article and Find Full Text PDFHypertension
January 2025
The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Newtown, Australia (L.C., S.Y., N.E., M.W., T.L., Y.G., C.S.A., K.H., X.C., R.P.).
Background: The association between systolic blood pressure and all-cause mortality differs between frail and nonfrail individuals, highlighting uncertainties about the effectiveness of antihypertensive treatments in frail populations.
Methods: Using data from the SHEP trial (Systolic Hypertension in the Elderly Program), a baseline frailty index (FI), including 55 variables, was constructed. Fine-Gray subdistribution hazard models and Cox proportional hazards regression models were used to explore the association between baseline FI and the risks of stroke, cardiovascular disease, and all-cause death, as well as to examine whether the impact of antihypertensive treatment on these outcomes was modified by baseline FI.
Cardiovasc Diabetol
January 2025
Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: Diabetic myocardial disorder (DbMD, evidenced by abnormal echocardiography or cardiac biomarkers) is a form of stage B heart failure (SBHF) at high risk for progression to overt HF. SBHF is defined by abnormal LV morphology and function and/or abnormal cardiac biomarker concentrations.
Objective: To compare the evolution of four DbMD groups based on biomarkers alone, systolic and diastolic dysfunction alone, or their combination.
NPJ Biofilms Microbiomes
January 2025
Department of Health and Genomics, FISABIO Foundation, Valencia, Spain.
We have previously demonstrated that subgingival levels of nitrate-reducing bacteria, as well as the in vitro salivary nitrate reduction capacity (NRC), were diminished in periodontitis patients, increasing after periodontal treatment. However, it remains unclear if an impaired NRC in periodontitis can affect systemic health. To determine this, the effect of nitrate-rich beetroot juice (BRJ) on blood pressure was determined in 15 periodontitis patients before and 70 days after periodontal treatment (i.
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