Serovars of Mycobacterium avium complex isolated from patients in Denmark.

J Clin Microbiol

Mycobacteria Department, Statens Seruminstitut, Copenhagen, Denmark.

Published: November 1994

Danish isolates of Mycobacterium avium complex were serotyped by the use of seroagglutination. The most prevalent serovars among patients with AIDS (n = 89) were 4 and 6, while among non-AIDS patients the most prevalent serovars were 1, 6, and 4, with no major differences between those in patients with pulmonary disease (n = 65) and those in patients with lymph node infection (n = 58). The results suggest a Scandinavian distribution of serovars with a predominance of serovar 6 and fail to demonstrate any selective protection against different serovars by Mycobacterium bovis BCG vaccination.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC264184PMC
http://dx.doi.org/10.1128/jcm.32.11.2880-2882.1994DOI Listing

Publication Analysis

Top Keywords

serovars mycobacterium
8
mycobacterium avium
8
avium complex
8
prevalent serovars
8
serovars
5
patients
5
complex isolated
4
isolated patients
4
patients denmark
4
denmark danish
4

Similar Publications

This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2023 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and 10 non-MSs. Key statistics on zoonoses and zoonotic agents in humans, food, animals and feed are provided and interpreted historically. In 2023, the first and second most reported zoonoses in humans were campylobacteriosis and salmonellosis, respectively.

View Article and Find Full Text PDF

Previous investigations have explored the involvement of wolves in parasitic and viral diseases, but data on the zoonotic bacteria are limited. The aim of this study was to assess the occurrence of bacterial zoonotic agents in 16 wolf () fecal samples collected in a protected area in Central Italy. spp.

View Article and Find Full Text PDF
Article Synopsis
  • The GID/CTLH complex, an E3 ubiquitin ligase in eukaryotes, plays a role in various biological processes but its function in anti-microbial defenses is not well understood.
  • Researchers conducted a genetic screen to find host factors that limit Mycobacterium tuberculosis growth in macrophages, identifying five members of the GID/CTLH complex as significant in controlling both Mtb and Salmonella growth.
  • The study revealed that knockout of the GID/CTLH complex enhances macrophage resistance to cell death from Mtb and boosts anti-microbial mechanisms, indicating that this complex normally inhibits host defenses against intracellular bacterial infections.
View Article and Find Full Text PDF

Typhimurium infection inhibits macrophage IFNβ signaling in a TLR4-dependent manner.

Infect Immun

October 2024

Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.

Article Synopsis
  • * STm infection inhibits IFNβ signaling without affecting IFNγ signaling, and this inhibition is linked to Toll-like receptor 4 (TLR4), as lipopolysaccharide (LPS) can independently block IFNβ-mediated signaling.
  • * The research reveals decreased levels of the IFNα/β receptor 1 (IFNAR1) on macrophage surfaces in response to LPS, suggesting a mechanism for the observed
View Article and Find Full Text PDF

Humanized Mouse Models of Bacterial Infections.

Antibiotics (Basel)

July 2024

Center for Musculoskeletal Research, Department of Orthopaedics, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.

Article Synopsis
  • Bacterial infections are a major global health issue, leading to high rates of illness and death, especially with the rise of multidrug-resistant strains.
  • Traditional mouse models do not accurately mimic human bacterial infections due to their differences in immune responses and disease manifestation, such as the lack of specific symptoms like lung granulomas.
  • Humanized mouse models have been developed over the past two decades to better represent human immune systems, providing more relevant insights into immune responses and helping to improve treatments for bacterial infections.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!