AV delay optimization and management of DDD paced patients with dilated cardiomyopathy.

Pacing Clin Electrophysiol

Divisione di Cardiologia, Arcispedale S. Anna, Ferrara, Italy.

Published: November 1994

Ten DDD paced patients, suffering from dilated cardiomyopathy in the NYHA functional classes III or IV were studied by means of Doppler echocardiography at different programmed values of atrioventricular (AV) delay (200, 150, 120, 100, and 80 msec). The following variables were evaluated: LV diameter, ejection fraction, mitral and aortic flow velocity integrals, and stroke volume. During VDD pacing, a resting AV delay associated with the best diastolic filling and systolic function was identified and programmed individually. Shortening of the AV delay to about 100 msec was associated with a gradual and progressive improvement. Further decrease caused an impairment of systolic function. The patients were clinically and hemodynamically reevaluated after 2 months of follow-up. A reduction of NYHA class and an improvement of LV function were consistently found. The reported data suggest that programming of an optimal AV delay may improve myocardial function in DDD paced patients with congestive heart failure. This result may be the consequence of an optimization of left ventricular filling and a better use of the Frank-Starling law.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8159.1994.tb03785.xDOI Listing

Publication Analysis

Top Keywords

ddd paced
12
paced patients
12
dilated cardiomyopathy
8
100 msec
8
systolic function
8
delay
5
delay optimization
4
optimization management
4
management ddd
4
patients
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!