Adults with autism and young children first learned to match one-element comparison stimuli to two-element sample stimuli. Test conditions then examined whether each of the individual sample elements (a) controlled selections of the comparison stimuli to which they were related during training, (b) were interchangeable with one another as either sample or comparison stimuli, and (c) were interchangeable with the original comparison stimuli. Test data were positive and suggested the formation of three-member stimulus classes. Subsequent experiments demonstrated the formation of four-member classes by (a) adding novel stimuli by training outside the original context; (b) adding novel stimulus elements to the two-element samples used during baseline training; and (c) training with three-element rather than two-element sample stimuli from the outset. Results suggest that acquisition of stimulus classes may be one of the benefits of broad rather than restricted attention to the components of complex stimuli.
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http://dx.doi.org/10.1007/BF02172284 | DOI Listing |
Psychon Bull Rev
January 2025
Department of Psychology, Minnesota State University, Mankato, MN, USA.
Although a large body of work has explored the mechanisms underlying metaphor comprehension, less research has focused on spontaneous metaphor production. Previous research suggests that reasoning about analogies can induce a relational mindset, which causes a greater focus on underlying abstract similarities. We explored how inducing a relational mindset may increase the tendency to use metaphors to describe topics.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge, United Kingdom.
Background: Frontotemporal dementia (FTD) and Progressive Supranuclear Palsy (PSP) have distinct molecular pathologies, with Tau and TDP43 aggregation, and distinct patterns of regional brain atrophy. However, they share the synaptotoxicity of protein aggregation, and neurotransmitter loss (including GABA), which contribute to clinical and neurophysiological similarities. Defining the relationships between synaptic loss, network physiology and cognition builds bridges between preclinical and clinical studies, and facilitates early phase trials.
View Article and Find Full Text PDFBehav Brain Res
December 2024
CERVO Brain Research Centre, 2301 Av. D'Estimauville, Québec City, QC, Canada, G1E 1T2; Department of Psychiatry and Neurosciences, Faculty of Medicine, Université Laval, Québec City, QC, Canada. Electronic address:
During early development, zebrafish larvae exhibit stereotypical behaviors, which rapidly become more complex. Thus, generating mutant transgenic lines that maintain transparency throughout their larval stage and that can be used to record brain activity has offered strategic opportunities to investigate the underlying neural correlates of behavior establishment. However, few studies have documented the sensorimotor profile of these lines during larval development.
View Article and Find Full Text PDFPLoS Comput Biol
January 2025
Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America.
Characterizing neuronal responses to natural stimuli remains a central goal in sensory neuroscience. In auditory cortical neurons, the stimulus selectivity of elicited spiking activity is summarized by a spectrotemporal receptive field (STRF) that relates neuronal responses to the stimulus spectrogram. Though effective in characterizing primary auditory cortical responses, STRFs of non-primary auditory neurons can be quite intricate, reflecting their mixed selectivity.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2024
Department of Biomedical Engineering, University of Rochester, Rochester, New York 14620, USA.
Profile-analysis experiments measure the ability to discriminate complex sounds based on patterns, or profiles, in their amplitude spectra. Studies of profile analysis have focused on normal-hearing listeners and target frequencies near 1 kHz. To provide more insight into underlying mechanisms, we studied profile analysis over a large target frequency range (0.
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