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Genomic traits of multidrug resistant enterotoxigenic isolates from diarrheic pigs.
Front Microbiol
August 2023
College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Article Synopsis
- The study examined 19 enterotoxigenic E. coli (ETEC) isolates from diarrhea in pigs at large-scale farms in Sichuan, China, using whole-genome sequencing and bioinformatics to understand their traits and resistance patterns.
- The isolates showed significant resistance to multiple antibiotics but were sensitive to a few, with notable genetic diversity and the presence of harmful virulence factors, some of which are linked to human diseases.
- The prevalence of hybrid ETEC/STEC isolates and resistance genes on plasmids raises concerns about potential public health risks and emphasizes the need for better control strategies in both animal and human health contexts.
Lentils and Yeast Fibers: A New Strategy to Mitigate Enterotoxigenic (ETEC) Strain H10407 Virulence?
Nutrients
May 2022
Center for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Dietary fibers exhibit well-known beneficial effects on human health, but their anti-infectious properties against enteric pathogens have been poorly investigated. Enterotoxigenic (ETEC) is a major food-borne pathogen that causes acute traveler's diarrhea. Its virulence traits mainly rely on adhesion to an epithelial surface, mucus degradation, and the secretion of two enterotoxins associated with intestinal inflammation.
View Article and Find Full Text PDFSubtractive genomic approach toward introduction of novel immunogenic targets against Clostridioides difficile: Thinking out of the box.
Microb Pathog
January 2022
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran; Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran. Electronic address:
Clostridioides difficile is one of the major causatives of nosocomial infections worldwide. Antibiotic-associated diarrhea, pseudomembranous colitis, and toxic megacolon are the most common forms of C. difficile infection (CDI).
View Article and Find Full Text PDFAlternating hemiparesis in the context of hemolytic uremic syndrome and COVID-19 positivity.
Epilepsy Behav Rep
July 2021
Division of Critical Care and Hospital Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Hemiparesis has been reported in hemolytic uremic syndrome (HUS), however electrophysiological findings associated with this syndrome have not been well-characterized, and alternating hemiparesis presentations have not been reported. We present detailed electrophysiological and clinical findings in a case of alternating hemiparesis corresponding to alternating focal contralateral delta slowing on prolonged EEG monitoring in a case of HUS with COVID-19 positivity. A 24-year-old woman was admitted with bloody diarrhea, acute kidney injury, and focal seizures initially presumed due to Escherichia coli 0157:H7 Shiga-like toxin-related hemolytic uremic syndrome (ST-HUS).
View Article and Find Full Text PDFPrevalence and characterization of virulence genes in Escherichia coli isolated from piglets suffering post-weaning diarrhoea in Shandong Province, China.
Vet Med Sci
February 2020
School of Life Sciences, Shandong First Medical University, Tai'an City, China.
The present study was performed to investigate the prevalence and characteristics of virulence genes in Escherichia coli (E. coli) isolated from piglets suffering post-weaning diarrhoea (PWD) in Shandong Province, China. The standard bacteriological method was used to isolate and identify E.
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