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[Gastrointestinal hamartomatous inverted hyperplastic polyps: a clinicopathological analysis of ten cases].
Zhonghua Bing Li Xue Za Zhi
February 2025
Department of Pathology, the First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
To investigate the clinicopathological features, diagnosis, genetic alterations, and biological behaviors of hamartomatous inverted hyperplastic polyp (HIHP) in the gastrointestinal tract. The clinical, sonographic, endoscopic and pathologic data of 10 HIHP cases diagnosed at the First Affiliated Hospital of Air Force Medical University, Xi'an, China from January 2013 to March 2024 were collected. Their clinicopathological features and histological morphology were analyzed.
View Article and Find Full Text PDFAdenocarcinoma on retrorectal cystic hamartoma: An illustrative image for a very rare diagnosis.
Semin Oncol
December 2024
Department General and Digestive Surgery Coloproctology, Hospital Universitario de Burgos, Burgos, Spain.
Retrorectal cystic hamartoma (also known as tailgut cyst) is a congenital lesion that originates from debris from the embryonic caudal intestine. Incidentally diagnosed in more than half of cases, the treatment of choice is surgical resection. It is a very rare pathology whose oncological transformation constitutes a true pathological rarity.
View Article and Find Full Text PDFBenign Tumors and Tumor-Like Conditions of Ampulla and Small Intestine: The PathologyOutlines.com Review.
Int J Surg Pathol
October 2024
PathologyOutlines.com Owner and Founder.
Article Synopsis
- The small intestine and ampulla can develop various benign tumors and tumor-like diseases that may resemble cancer, highlighting the need for pathologists to have a comprehensive understanding of these conditions.
- Key examples of these benign issues include Brunner gland lesions, different types of polyps, and various mesenchymal proliferations like inflammatory fibroid polyps and leiomyomas.
- The review aims to clarify the histopathological features of these benign conditions to aid pathologists in making accurate diagnoses and differentiating them from malignant tumors.
A giant Brunner's gland hamartoma: a rare cause of upper gastrointestinal bleeding.
Acta Gastroenterol Belg
August 2024
Gastroenterology Department, Hospital Garcia de Orta, Almada, Portugal.
Cowden Syndrome: A Rare Cause of Intestinal Polyposis.
Cureus
July 2024
Department of Pediatrics, Salmaniya Medical Complex, Manama, BHR.
Article Synopsis
- - Cowden syndrome (CS) is a rare genetic disorder that leads to multiple hamartomata lesions from all embryonic layers, primarily affecting the gastrointestinal system and leading to an increased risk of certain cancers, including thyroid and breast cancer.
- - The initial symptoms of CS typically include mucocutaneous issues like trichilemmomas and oral papillomas, making early diagnosis and management crucial for improving patient outcomes.
- - A case study is presented involving a Bahraini child with macrocephaly and extensive intestinal polyposis, with genetic testing confirming CS through a pathogenic variant in the PTEN gene.
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