The penetration into the eye of fluorescein from a normal drop was found to increase with age and averaged twelve times more in the elderly than in the young. Examination of the literature suggests that this is a result of a greater contact time with the cornea rather than a rise in epithelial permeability.
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http://dx.doi.org/10.1089/jop.1994.10.521 | DOI Listing |
Int J Colorectal Dis
January 2025
Hereditary Digestive Tract Tumors Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori, Via Giacomo Venezian 1, 20133, Milan, Italy.
Purpose: In this study, we investigated the progression of high-grade dysplasia (HGD)/CRC in patients with hereditary colorectal cancer syndromes (HCSS) and concomitant inflammatory bowel diseases (IBDs).
Methods: We described the natural history of a series of patients with confirmed diagnosis of hereditary colorectal cancer syndromes (HCCSs) and concomitant IBDs who were referred to the Hereditary Digestive Tumors Registry at the Fondazione IRCCS Istituto Nazionale dei Tumori of Milan.
Results: Between January 1989 and April 2024, among 450 patients with APC-associated polyposis and 1050 patients with Lynch syndrome (LS), we identified six patients with IBDs (five with UC, one with ileal penetrating CD) and concomitant HCCSs (five with LS, one with APC-associated polyposis).
Diagnostics (Basel)
January 2025
Elmhurst Hospital Center, Trauma Unit, Department of Surgery, NYC Health & Hospitals, New York, NY 11373, USA.
: Fluctuations in sodium levels (SLs) may increase mortality, severity, and prolonged length of stay (LOS) in critically ill patients. We aim to study the effect of SL on various clinical outcomes in patients with severe traumatic brain injury (TBI). : This is a single-center, retrospective study of patients with severe TBI from 1 January 2020 to 31 December 2023, inclusive.
View Article and Find Full Text PDFProximal humeral fractures (PHF), ranking as the third most common osteoporotic fractures, pose a significant challenge in management. With a rising incidence in an aging population, controversy surrounds surgical versus nonoperative treatments, particularly for displaced 3- and 4-part fractures in older patients. Locking plates (LP) and proximal intramedullary nails (PHN) are primary choices for surgical intervention, but both methods entail complications.
View Article and Find Full Text PDFTrauma Surg Acute Care Open
January 2025
Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Background: Operative mortality for high-grade liver injury (HGLI) remains 42% to 66%, with near-universal mortality after retrohepatic caval injury. The objective of this study was to evaluate mortality and complications of operative and nonoperative management (OM and NOM) of HGLI at our institution, characterized by a trauma surgery-liver surgery collaborative approach to trauma care.
Methods: This was an observational cohort study of adult patients (age ≥16) with HGLI (The American Association for Surgery of Trauma (AAST) grades IV and V) admitted to an urban level I trauma center from January 2010 to November 2021.
Front Med (Lausanne)
January 2025
Dalian Medical University, Dalian, China.
Background: The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.
Methods: The clinical records of 359 patients (394 eyes) who underwent corneal transplantation at the Department of Keratoconus of the Third People's Hospital of Dalian from January 2019 to December 2023 were retrospectively analyzed. The data included patients' age, gender, occupation, diagnosis, surgical procedure, postoperative immune rejection, and neovascularization.
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