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Clinical Advantages of Phlebotomy: An Umbrella Review of Meta-Analyses.
Iran J Public Health
December 2024
Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Phlebotomy has been used as a non-pharmacological treatment for different types of diseases, regarding the philosophy of humors in traditional medicines, such as Persian Medicine. However, according to the narrow-approved indications for phlebotomy in Western Medicine, we aimed to systematically summarize high-level of evidence on safety and efficacy of phlebotomy in treatment of human diseases.
Methods: In this umbrella review, to identify meta-analysis studies of clinical trials on phlebotomy, four electronic databases, including PubMed, web of science, Scopus, and Cochran library were searched until Jun 18, 2022 with relevant keywords for 'phlebotomy' and 'meta-analysis' according to PRISMA guidelines and PICO questions.
Acute Toxicity With Lactic Acidosis Associated With Cannabinoid Gummies.
Cureus
October 2024
Internal Medicine/Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.
Article Synopsis
- The use of marijuana and its products is common in the U.S., but they can lead to serious health issues, including toxic reactions from edible forms with uncertain dosages.
- A case report detailed a patient who consumed too many cannabinoid gummies, leading to symptoms like lethargy, agitation, vomiting, high heart rate, high blood pressure, and respiratory failure.
- The patient received supportive care in the ICU, and it’s important for doctors to consider cannabis toxicity as a potential cause of symptoms like lactic acidosis when patients show these signs in the emergency room.
Clinical characteristics and prognosis of steroid-resistant nephrotic syndrome in children: a multi-center retrospective study.
Ital J Pediatr
November 2024
Department of Pediatrics, The First Hospital of Guangxi Medical University, Nanning, China.
Background: This study investigated the factors influencing the prognosis of children with steroid-resistant nephrotic syndrome (SRNS) in patients from the Guangxi region.
Methods: We retrospectively analyzed clinical and pathological data of 279 patients with SRNS from six tertiary hospitals in Guangxi. Clinical data were compared between initial (I-SRNS) and secondary (S-SRNS) steroid resistance subgroups and Cox regression analysis was used to determine risk factors for chronic kidney disease (CKD) and CKD stage 5 (CKD5) in patients with SRNS.
Calcium Chaos in Sarcoidosis: A Tale of Severe Hypercalcemia's Diagnostic Challenge.
Cureus
March 2024
Pulmonary and Critical Care Medicine, Saint Peter's University Hospital/Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Sarcoidosis is a systemic inflammatory condition characterized by noncaseating granulomas. Lung involvement is typical, while extrapulmonary manifestations, notably lymphadenopathy, are observed in a significant proportion of cases. The etiology involves complex interactions among immune cells and mediators, resulting in granuloma formation capable of independently producing 1,25-dihydroxyvitamin D, leading to unregulated hypercalcemia and hypercalciuria.
View Article and Find Full Text PDFThe prognostic importance of the pan-immune-inflammation value in patients with septic shock.
BMC Infect Dis
January 2024
Department of Critical Care, Marmara University Faculty of Medicine, Pendik, Istanbul, 34899, Turkey.
Introduction: The purpose of this study was to determine whether the pan-immune-inflammation value (PIV), a novel biomarker combining neutrophil platelet, monocyte, and lymphocyte counts, some of the most widespread indicators of systemic inflammation, can predict mortality and prognosis in patients admitted to the intensive care unit (ICU) with septic shock.
Method: This prospective study was performed with 82 patients aged 18 or over admitted to a tertiary ICU with diagnoses of septic shock. Patients with hematological disease and neutropenia were excluded.
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