Relapsing polychondritis is a rare, presumably inflammatory autoimmune disorder affecting cartilagenous structures throughout the body. The ears, nose, joints, eyes and the respiratory tract are most frequently involved. The main ocular manifestations are episcleritis and scleritis, conjunctivitis, iridocyclitis and chorioretinitis, cataract and corneal infiltrates and melting. Extraocular signs and symptoms often are indicative of the diagnosis. Therapy includes systemic steroids, immunosuppressive drugs and dapsone. Three case histories are reported and the literature of ocular manifestations of relapsing polychondritis is reviewed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF01204793 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Retinal Vasculitis as a Rare Presentation of Microscopic Polyangiitis.
Cureus
December 2024
Internal Medicine, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Microscopic polyangiitis (MPA) is a rare, autoimmune, small-vessel vasculitis usually described with the presence of perinuclear antineutrophil cytoplasmic antibodies (p-ANCA). It encompasses a broad spectrum of clinical features, including fatigue, weight loss, fever, arthralgia, skin lesions, and involvement of the lungs or kidneys. Ocular manifestations, however, are extremely rare.
View Article and Find Full Text PDFHiding in plain sight: A rare case of ocular thelaziasis.
Med J Armed Forces India
July 2024
Air Officer Commanding, 5 Air Force Hospital, Jorhat, India.
A 65-year-old male patient presented to eye outpatient department of a zonal hospital in North Eastern India with complaints of diminution of vision for 1-year duration. On ocular examination, his unaided visual acuity was 6/36 right eye and 6/12 left eye. He was diagnosed as a case of immature senile cataract with nuclear sclerosis grade 2+ in the right eye and immature senile cataract with nuclear sclerosis grade 1+ in the left eye, with no other ocular or systemic findings.
View Article and Find Full Text PDFCharacteristics of ocular findings of patients with coronavirus disease 2019 in China.
Front Med (Lausanne)
January 2025
Eye Hospital, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Purpose: This study aimed to report the ocular manifestations in individuals with coronavirus disease 2019 (COVID-19) and investigate any correlation between the occurrence of ocular symptoms and systemic symptoms.
Methods: A retrospective electronic survey was conducted among the general public in northern China from December 2022 through February 2023. Inclusion criteria for COVID-19 was confirmed testing positive via a polymerase chain reaction (PCR) test or testing positive for COVID-19 via an antigen kit.
Exocrine pancreatic insufficiency as an unusual extrarenal manifestation of proximal renal tubular acidosis associated with a novel SLC4A4 mutation.
Pediatr Nephrol
January 2025
Department of Pediatric Nephrology, Istanbul University- Cerrahpasa, Cerrahpasa Faculty of Medicine, 34098, Istanbul, Turkey.
Autosomal recessive proximal renal tubular acidosis (AR-pRTA) with ocular abnormalities is a rare syndrome caused by variants in the SLC4A4 gene, which encodes Na/HCO3 cotransporter (NBCe1). The syndrome primarily affects the kidneys, but also causes extra-renal manifestations. Pancreatic type NBCe1 is located at the basolateral membrane of the pancreatic ductal cells and together with CFTR chloride channel, it is involved in bicarbonate secretion.
View Article and Find Full Text PDFRetinal biomarkers for the risk of Alzheimer's disease and frontotemporal dementia.
Front Aging Neurosci
January 2025
Department of Neurology, West China Hospital of Sichuan University, Chengdu, China.
Purpose: Differentiating between Alzheimer's disease (AD) and frontotemporal dementia (FTD) can be challenging due to overlapping cognitive and behavioral manifestations. Evidence regarding non-invasive and early-stage biomarkers remains limited. Our aim was to identify retinal biomarkers for the risk of AD and FTD in populations without dementia and explore underlying brain structural mechanisms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!