The urine ALb, serum and urine beta 2-m, IgG, and THP were serially determined with radioimmunoassay to assess the renal functions during various stages of burn in 52 patients with TBSA over 30% (mean +/- s 58.4% +/- 18.88%). It was found that the urine levels of ALb, IgG, and THP and the serum and urine levels of beta 2-m were remarkably increased and that the serum levels of IgG were decreased after burns. Our study suggested that the measurements of urine ALb, serum and urine beta 2-m, IgG, and THP using radioimmunoassay were sensitive in assessing renal glomerular permeability and tubular functions after burn. It is presumed that such methods might be used to help identify the location, the extent, and the severity of the renal abnormalities and provide valuable information about the differential diagnosis and the prognosis of the renal damage in patients with extensive burns.
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