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It has been established that the degree of ionization of serum calcium increases with the progression of hypertensive disease (HD) concurrently with the elevation of the level of calcitoninemia. Concentrations of parathyroid hormone remain unchanged at early stages of HD and it is not until hypertrophy of the left ventricle becomes clinically apparent that they begin to increase. The data obtained will, we believe, help in accounting for the features of the clinical course of variant forms of hypertrophy of left ventricle in patients with hypertensive disease.

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