[The glutathione content and glutathione-S-transferase activity in the organs and blood of rats following chronic irradiation at low doses].

The effect of chronic low dose-rate irradiation with X-rays up to total doses of 2.58, 5.16, 6.46, 7.75, 10.32, 12.92 mC/kg on glutathione content and glutathione-S-transferase activity in Wistar rats organs, different by radiosensitivity, was studied 1 h after exposure. It has been shown that level of oxidized and reduced glutathione forms was not changed after exposure to 2.58 mC/kg, was enhanced in kidney and brain tissues after exposure to 5.16 and 6.46 mC/kg and was decreased in brain, lungs, small intestines and blood serum after ray exposures to higher doses. Inhibition of glutathione-S-transferase activity was found in liver, kidneys and spleen.