[Mycoses in oncologic patients].

Lately the frequency of fungal infections in oncological patients considerably increased. The cause is a decreased immune status and in particular decreased immunity against fungal infections in oncological patients because of the oncological disease and aggressive treatment. In the patients treated with immunodepressants the frequency of Candida vegetating on the skin and in open cavities was higher. Fungi were isolated from the pathological materials of 8.9 per cent of the patients in 1981, 12 per cent in 1990, 17 per cent in 1991 and 24 per cent in 1992. Candida were more frequent than other taxa. The frequency of Candida amounted to 92-97 per cent of all the fungal isolates. This stipulated for the necessity of not only an adequate use of antimycotics in the treatment of fungal infections and more often mixed bacterial and fungal infections but also the prophylaxis of fungal infections.