In rats which had sustained clinical death and resuscitation, which were compatible with apparent complete recovery of the neurological status, responsiveness of the autonomic nervous system was studied from the changes occurred in blood pressure, heart and respiration rates within 2 hours of restrictive exercise at some stages of the late postresuscitation period--1.5-2, 3.5, and 4.5 months after reanimation. The responsiveness of the autonomic nervous system was compared with changes in conditioned reflex performance (a situational food instrumental conditioned reflex (SFICR)). There were progressive stage-specific changes in the responsiveness of the autonomic nervous system as an increasing trend towards to persistent hypertension during restrictive exercise. The functional failure of the autonomic nervous system during a postresuscitation process coincided with autonomic nervous abnormalities which were detected in responses to acute or long-term stresses, showing more profound SFICR changes than in intact animals.
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