The aortal valve anomaly was studied in 179 patients using intraoperative examination and morphometry and histologic investigation of an excised cusps. The pronounced form and size asymmetry of the valve cusps revealed in Laubry-Pezzi syndrome and also histologic signs of their primary hemodynamic traumatization causes the predisposition for the progress of the aortal valve insufficiency, development of infectious endocarditis and rheumatism.

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