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Article Synopsis
- Epitope spreading refers to the process where the immune response expands from an initial target (like a specific protein) to other similar or related targets within the same tissue or area.
- Subacute thyroiditis (SAT) and pemphigus vulgaris are autoimmune conditions that can occur simultaneously, suggesting a shared immune response mechanism.
- The molecular link between SAT and pemphigus vulgaris may involve epitope spreading, where the immune system's focus on thyroid proteins leads to the targeting of skin proteins, resulting in symptoms of both diseases.
Pemphigus in Goa.
J Indian Med Assoc
October 1994
Department of Dermatology, Venereology and Leprology, Goa Medical College.
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