AI Article Synopsis
- The study investigates protein synthesis in rat decidual tissue using labelled methionine and finds an active protein production process in the endometrium.
- Decidual cells in different areas of the endometrium synthesize proteins at varying rates, with mesometrial cells showing a higher incorporation rate of methionine.
- The research identifies qualitative changes in endometrial proteins at different developmental stages and discusses how these changes relate to the cellular structure and gene expression in the decidualizing endometrium.
Article Abstract
Incorporation, in vitro, of labelled methionine into proteins of artificially induced decidual tissue shows the presence of an active protein synthetic machinery in the decidualising endometrium of rats. During the progressive phase, antimesometrial and mesometrial decidual cells, restricted to specific anatomical sites of the endometrium, synthesize proteins at varying rates and the rate of incorporation of methionine into proteins of mesometrial decidual cells is higher. Resolution of proteins on acrylamide gels following SDS electrophoresis shows qualitative changes in endometrial proteins at different stages of morphogenesis of decidual cells. Results are discussed in relation to characteristic morphological features of two decidual cell populations and differential gene expression in the decidualising endometrium.
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