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Progress on HIV and other sexually transmitted infections elimination among youth and adults across BRICS-plus countries: Results from the Global Burden of Disease Study 2021.
J Infect Public Health
December 2024
Department of Global Health, School of Public Health, Peking University, Beijing 100191, China; Institute for Global Health and Development, Peking University, Beijing 100191, China. Electronic address:
Background: Global strategies aim to eradicate HIV and other sexually transmitted infections (STIs) by 2030. We aim to assess HIV and other STIs morbidity trends from 1992 to 2021 across BRICS-plus (Brazil, Russia, India, China, South Africa, Egypt, Ethiopia, Iran, Saudi Arabia, and the United Arab Emirates), which accounts for nearly half of the world population.
Methods: HIV and other STIs morbidity estimates were derived from the Global Burden of Disease Study 2021.
Artificial intelligence-driven reverse vaccinology for vaccine: Prioritizing epitope-based candidates.
Front Mol Biosci
August 2024
Medical Biotechnology Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.
is the causative agent of the sexually transmitted disease gonorrhea. The increasing prevalence of this disease worldwide, the rise of antibiotic-resistant strains, and the difficulties in treatment necessitate the development of a vaccine, highlighting the significance of preventative measures to control and eradicate the infection. Currently, there is no widely available vaccine, partly due to the bacterium's ability to evade natural immunity and the limited research investment in gonorrhea compared to other diseases.
View Article and Find Full Text PDFCyclization increases bactericidal activity of arginine-rich cationic cell-penetrating peptide for .
Microbiol Spectr
September 2024
Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.
We previously reported that a linear cationic 12-amino acid cell-penetrating peptide (CPP) was bactericidal for . In this study, our objectives were to determine the effect of cyclization of the linear CPP on its antibacterial activity for and cytotoxicity for human cells. We compared the bactericidal effect of 4-hour treatment with the linear CPP to that of CPPs cyclized by a thioether or a disulfide bond on human challenge and multi-drug resistant (MDR) strains of grown in cell culture media with 10% fetal bovine serum (FBS).
View Article and Find Full Text PDFSexual Victimization and Sexually Transmitted Infections Among a Nationally Representative Sample of Adolescents and Young Adults in Haiti.
Arch Sex Behav
October 2024
Department of Sexology, Université du Québec à Montréal, QC, Canada.
Sexual assault victims are at major risk of being infected by sexually transmitted infections (STI). This article aims to examine and compare the prevalence of eight STIs (e.g.
View Article and Find Full Text PDFAntimicrobial Resistance in Gonorrhea.
Microb Drug Resist
July 2024
Ministry of Health, Rome, Italy.
Antimicrobial resistance is a global public health emergency. The World Health Organization recently highlighted the growing number of new sexually transmitted infections such as gonorrhea, syphilis, and Chlamydia, which are resistant to common antibiotics. The phenomenon is also on the rise due to increasing intercontinental travel.
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