Large quantities of oxygen free radicals can be generated on reperfusion of the ischemic myocardium. This phenomenon is probably responsible for a specific component of cell damage separate from ischemic injury and may blunt the beneficial effects of thrombolysis. Anti-free radical interventions may reduce the severity of this "reperfusion injury". However, reports of treatment failures indicate that reperfusion injury is a complex phenomenon, and suggest that the beneficial effects of treatment may be critically dependent on factors that are not clearly understood.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
beneficial effects
8
myocardial damage
4
damage ischaemia
4
ischaemia reperfusion
4
reperfusion large
4
large quantities
4
quantities oxygen
4
oxygen free
4
free radicals
4
radicals generated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!