AI Article Synopsis
- A study between 1987 and 1993 involved 762 kidney transplants in adults, comparing outcomes of 83 pediatric kidney donors to 100 adult donors.
- Recipients of pediatric kidneys experienced lower survival rates at 1 and 3 years compared to those with adult kidneys, along with higher rates of renovascular complications and acute rejection episodes.
- Despite these differences, serum creatinine levels were similar in both groups one year post-transplant, indicating comparable kidney function.
Article Abstract
Between July 1987 and July 1993, 762 renal allografts were transplanted into adult recipients at our institution. A total of 83 adults received cadaveric renal transplants from donors aged 5 months to 10 years, while 100 adults who received adult cadaver kidneys during the same period served as a comparison group. Cyclosporine based immunosuppression was used. No difference between the 2 groups was found with respect to recipient age, recipient sex, primary renal disease, HLA matching or the number of recipients with a previous transplant. Actual patient (graft) survivals at 1 and 3 years were 91% (77%) and 86% (68%), respectively, for recipients of pediatric kidneys compared to 99% (92%) and 90% (80%), respectively, for recipients of adult kidneys. Pediatric kidney recipients were more likely to encounter renovascular complications (13% versus 4%, p = 0.023) and more likely to have episodes of acute rejection (p = 0.018). Serum creatinine was equal in the 2 groups at 1 year following transplantation (p = 0.63).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00005392-199502000-00006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Endovascular Preparation With Innovative Custom-Made Stent-Graft Before Kidney Transplantation: The Solution for Patients With Hostile Iliac Calcification.
Transpl Int
January 2025
Service d'Urologie et de Transplantation, Hospices Civils de Lyon, Lyon, France.
The increasing age of patients with end-stage renal disease raises the issue of hostile arterial access for transplantation, with technical difficulties associated with clamping and suturing the iliac artery. Some of these patients - who theoretically represent those who would benefit the most from transplantation in terms of mortality - are contraindicated because of anatomical and medical issues. In this context, a specific endovascular device called EndoPreKiT (Endovascular Preparation for Kidney Transplantation) has been designed, enabling arterial access for transplantation via a mini-invasive procedure.
View Article and Find Full Text PDFSuccessful use of deceased donors with medically complex kidneys.
Transplant Rev (Orlando)
January 2025
Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, CA, United States of America.
The number of patients waiting for kidney transplants from deceased organ donors continues to increase. In this context, non-transplantation of acceptable kidneys is especially regrettable. Here, we review successful transplantation of deceased donor kidneys with anatomic abnormalities, intrinsic kidney diseases, and other ostensibly problematic conditions.
View Article and Find Full Text PDFThe liminal experience of awaiting for a cadaveric kidney donation: "I would not wish it on even my enemy!".
Soc Sci Med
December 2024
Ankara Etlik City Hospital, 06170, Ankara, Turkey. Electronic address:
This study aims to explore the concept of liminality in the lives of chronic kidney disease (CKD) patients in Turkiye who are undergoing dialysis while awaiting kidney transplants. The research focuses on how patients experience this transitional state, being between life stages, and how they cope with the uncertainty of their condition while aspiring for a transplant. The research involved in-depth, semi-structured interviews and participant observations of 34 dialysis patients who had been registered on the national organ waiting list for over five years.
View Article and Find Full Text PDFPostmortem/dynamic distribution of ethanol and its nonoxidative metabolites in poisoned rabbits.
Sci Rep
November 2024
School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, China.
Nonoxidative ethanol metabolites have been reported as ethanol biomarkers in clinical and forensic cases. However, their forensic toxicokinetics are still unclear. The study aimed to simultaneously research the postmortem distribution and dynamic distribution of ethanol and its nonoxidative metabolites in 62 poisoned rabbits.
View Article and Find Full Text PDFContinuous spinal anaesthesia for kidney transplantation in a lupus patient with severe mitral regurgitation: A case report.
Rev Esp Anestesiol Reanim (Engl Ed)
January 2025
Departamento de Cardiologia, Hospital Dr. Nélio Mendonça, Funchal, Portugal.
Anaesthesia for kidney transplant in a patient with severe mitral regurgitation is a real challenge given the need for judicious haemodynamic management to avoid pulmonary oedema and maximise reperfusion of the transplanted organ. This is the first experience described in the literature of continuous spinal anaesthesia in a patient with chronic severe mitral regurgitation undergoing cadaver donor kidney transplant. Transthoracic echocardiography monitoring was used during the procedure to avoid aggravating the patient's mitral regurgitation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!