Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
A free-radical initiator-based carrier-free smart nanobomb for targeted synergistic therapy of hypoxic breast cancer.
RSC Adv
January 2025
State Key Laboratory for New Textile Materials & Advanced Processing Technology, Wuhan Textile University Wuhan 430200 P. R. China
Thermodynamic therapy (TDT) is a promising alternative to photodynamic therapy (PDT) by absorbing heat through thermosensitive agents (TSAs) to generate oxygen-irrelevant highly toxic free radicals. Therefore, TDT can be a perfect partner for photothermal therapy (PTT) to achieve efficient synergistic treatment of anoxic tumors using a single laser, greatly simplifying the treatment process and overcoming hypoxia limitations. However, the issues of how to improve the stability and delivery efficiency of TSAs still need to be addressed urgently.
View Article and Find Full Text PDFEvaluation of a simulation-based ophthalmology education workshop for medical students: a pilot project.
BMC Med Educ
January 2025
Northern Ontario School of Medicine University, Thunder Bay, ON, Canada.
Background/aims: Ophthalmology is an under-represented specialty in many medical school curriculums resulting in reduced confidence in medical students and clinicians when dealing with eye conditions. Our study evaluates the impact of a simulation-based education (SBE) workshop to train medical students in ophthalmology.
Methods: Second-year medical students were invited to participate in a two-day (eight-hour) simulation-based ophthalmology workshop.
Dermatology education in U.S. ophthalmology residency: a survey of the program directors.
BMC Med Educ
January 2025
San Francisco School of Medicine, University of California, San Francisco, CA, USA.
Background: Many ocular conditions have associated dermatological findings. However, the inclusion of dermatology education in U.S.
View Article and Find Full Text PDFMultienergy Barrier Anti-/Deicing Surface with Excellent Photothermal Effect.
ACS Appl Mater Interfaces
January 2025
Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei University, Wuhan 430062, People's Republic of China.
Superhydrophobic surfaces are considered to be an effective method for anti-icing, but passive anti-icing alone is not as effective as it should be, so it is crucial to develop effective anti-icing techniques. In this study, a photothermal anti-icing structure with multienergy barriers was designed by combining active and passive anti-icing technologies and prepared by a three-step method of laser etching, hydrothermal growth of nanostructures, and chemical modification based on the Cassie-Baxter-Wenzel transition theory. The experimental results show that the static water contact angle of the prepared surface is up to 160°, the sliding angle is less than 3.
View Article and Find Full Text PDFPhotochemical bomb: Precision nuclear targeting to activate cGAS-STING pathway for enhanced bladder cancer immunotherapy.
Biomaterials
January 2025
Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou, 215000, China; Department of Urology, First Affiliated Hospital of Soochow University, Suzhou, 215006, China. Electronic address:
Activating the cGAS-STING pathway presents a promising strategy to enhance the innate immunity and combat the immunosuppressive tumor microenvironment. One key mechanism for triggering this pathway involves the release of damaged DNA fragments caused by nuclear DNA damage. However, conventional cGAS-STING agonists often suffer from limited nucleus-targeting efficiency and potential biotoxicity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!