A ten year experience gained in radiotherapy with radio modifiers of 480 patients with cancer of the cervix uteri and of 189 ones with endometrial cancer carried out at the Central Research Roentgeno-Radiological Institute of the Russian Academy of Medical Sciences is analyzed. Local administration of metromidasole with dimethysulfoxide essentially enhanced the detrimental effect of radiation on the tumor. This is reflected in a higher incidence of local control in radiotherapy of patients with cancer of the cervix and corpus uteri. A reduced incidence and degree of radiation injury to organs adjacent to the uterus was observed.
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