[Paraneoplastic edema syndromes in acute myelomonocytic leukemia: role of TNF-alpha and IL-6?].

Rev Med Interne

Service de médecine interne B, hôpital Carémeau, CHU, Nîmes, France.

Published: January 1995

We report the case of a 56 year-old man in remission of a Hodgkin's disease who had an acute myelomonocytic leukemia with major edemas. Chemotherapy temporarily allowed a concomitant regression of edemas, hyperleukocytosis and tumor necrosis factor and interleukin-6 levels which were initially elevated. We discuss the role of these two cytokines in endothelium permeability disorders.

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http://dx.doi.org/10.1016/s0248-8663(05)82183-6DOI Listing

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