The paper describes procedures for stratifying malariogenic areas that are homogeneous in the development pattern for epidemic stratum rises, which will be used to design a set of mathematical malaria spread models. The first stage of the procedures is to stratify P. falciparum and P. vivax malaria on phase planes. The morbidity rate of P. falciparum and P. vivax malaria was analyzed in the north-western areas of India in 1975-1990. Eighty-two observations provided 4 types of phase curves for tropic malaria, which form a polygon, a loop polygon, U-shaped ones and those without any specific signs and 4 groups of phase curves for P. vivax malaria and the U-shaped phase curve with a loop for P. vivax malaria. It is shown that there is a steady-state pattern of phase curve changes in 71%. It is suggested that the pattern of a phase curve can be a diagnostic characterization of the given area.
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January 2025
Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
The evolution of genetic diversity and population structure of Plasmodium vivax as malaria elimination approaches remains unclear. This study analyzed the genetic variation and molecular epidemiology of P. vivax from Yala Province in southern Thailand, an area in the pre-elimination phase.
View Article and Find Full Text PDFJ Vector Borne Dis
January 2025
ICMR-National Institute of Malaria Research (NIMR) Field Unit, Nadiad, Gujarat, India.
Worldwide elimination of malaria remains a challenge yet to be accomplished, and the domain of malaria relapse equally remains obtuse. Yet sophisticated cell culture and screening techniques and animal models are being constructed and molecular regulations are discovered in this intriguing discipline. An elaborate understanding of these schemes is mandatory to conceive effective therapeutic strategies.
View Article and Find Full Text PDFBMC Public Health
January 2025
Medical Microbiology Department, Faculty of Medical Sciences, Ibb University, Ibb, Yemen.
Background: Malaria is one of the important diseases that threatens the global health system, especially in developing countries, including Yemen. Based on surveillance data, this analysis aimed to assess the trend of malaria in Yemen over the last sixteen years from 2006 to 2021.
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BMC Infect Dis
January 2025
Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-Gu, Seoul, 03722, Republic of Korea.
Background: Although Plasmodium vivax (P. vivax) malaria is in the pre-elimination phase in the Republic of Korea (ROK), it continues to affect children and adolescents, who account for approximately 4-6% of the 300 to 500 annual cases. Despite this, research focusing on P.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
School of Public Health, National Defense Medical Center, Taipei City, Taiwan.
Although the World Health Organization (WHO) certified Taiwan as being malaria-free in 1965, there are reports of a few imported cases each year by travelers who visit malaria-endemic areas. This study examined the epidemiology of imported malaria cases in Taiwan from 2014 to 2020, utilizing national surveillance data from the Taiwan Centers for Disease Control. Malaria cases were confirmed through the application of standard laboratory methods.
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