Objective: We describe a newly defined syndrome of protracted febrile myalgia in patients with familial Mediterranean fever (FMF).
Methods: Fourteen patients with FMF were admitted with an attack of severe disabling myalgia accompanied by fever, high erythrocyte sedimentation rate, and hyperglobulinemia, lasting up to 6 weeks.
Results: Unlike in the classical manifestations of FMF response to corticosteroids therapy was prompt.
Conclusion: Protracted febrile myalgia is an uncommon dramatic manifestation of FMF that may occur despite colchicine therapy and requires treatment with corticosteroids.
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