AI Article Synopsis
- A study of 32 mixed cryoglobulinaemia (MC) patients revealed that 34.3% experienced audiovestibular disturbances, including a notable incidence of bilateral sensorineural hearing loss and altered vestibular function.
- Seven patients (22%) showed hearing loss, and another seven had abnormal vestibular test results.
- The research suggests that these issues may stem from immune complex-related damage to the inner ear, emphasizing the need to consider audiovestibular disturbances as part of MC's broader impact on the body.
Article Abstract
In order to evaluate the nature and prevalence of audiovestibular disturbances in mixed cryoglobulinaemia (MC), 32 consecutive MC patients were studied by a wide audiological and vestibular examination. Pure tone audiometry, impedance audiometry, brainstem response audiometry and vestibular function were performed. Patients with a previous history of ear damage due to other well-known agents were excluded from the study. In MC patients we found a rather frequent audiovestibular involvement (34.3%). Bilateral sensorineural hearing loss was found in seven MC patients (22%) and altered vestibular function test values in other seven subjects (22%). Moreover, anamnestic and clinical data revealed a high incidence of benign positional paroxysmal vertigo in our MC series. We can suppose that immune complex-mediated microvascular involvement of the labyrinthine vessels may be responsible for inner ear damage in MC. Thus, audiovestibular disturbances may be included among various organ involvement of the MC.
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| http://dx.doi.org/10.1093/rheumatology/34.4.370 | DOI Listing |
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