Background: The pathogenesis of anorexia nervosa (AN) is controversial.
Method: A retrospective case series was studied to investigate the post-viral onset of AN.
Results: Four consecutive in-patients with severe restrictive AN spontaneously volunteered histories of 'glandular fever'-like illnesses immediately before the onset of their eating disorder. This association has not previously been described. Possible pathogenic pathways include both non-specific and specific viral disruptions in central homeostasis, particularly involving corticotrophin-releasing hormone (CRH) regulation.
Conclusion: Such mechanisms are speculative, but biologically and historically plausible.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1192/bjp.166.3.386 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Complications of Long COVID: Unraveling a Case of Very-Late-Onset Myasthenia Gravis.
Cureus
September 2024
Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Myasthenia gravis (MG) is defined as an autoimmune neuromuscular disorder where autoantibodies disrupt synaptic transmission at the neuromuscular junction by targeting the acetylcholine receptor (AChR), muscle-specific kinase (MuSK), or other proteins related to the AChR complex. This disruption leads to characteristic muscle weakness and rapid fatigability. Clinically, MG is classified based on the age of onset into three distinct categories: early-onset MG (younger than 50 years), late-onset MG (between 50 and 64 years), and very-late-onset MG (65 years and older).
View Article and Find Full Text PDFChildhood cancer care beyond the 'six common and curable types': A comparative case series on acute myeloid leukemia in Kenya and the Netherlands.
Asia Pac J Oncol Nurs
October 2024
Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
Article Synopsis
- Over 400,000 children develop cancer annually, with survival rates in high-income countries (75-80%) significantly higher than in low- and middle-income countries (less than 30%).
- The case report examines two pediatric cases of acute myeloid leukemia (AML) from Kenya and the Netherlands, emphasizing the differences and similarities in their diagnostic journeys and treatments.
- Both patients faced challenges like febrile neutropenia but successfully completed treatment and entered remission, showcasing the potential for effective AML care even in resource-limited environments and highlighting the need to expand focus beyond commonly recognized curable cancers.
New-Onset Chronic Musculoskeletal Pain Following COVID-19 Infection Fulfils the Fibromyalgia Clinical Syndrome Criteria: A Preliminary Study.
Biomedicines
August 2024
Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds LS7 4SA, UK.
New-onset chronic musculoskeletal (MSK) pain (>3 months duration) is a common symptom of post-COVID-19 syndrome (PCS). This study aimed to characterise new-onset chronic MSK pain in patients with PCS and its overlap with Fibromyalgia Syndrome (FMS). We enrolled patients with new-onset chronic MSK pain post-COVID-19 and assessed the nature of the pain and associated symptoms using the C19-YRS (Yorkshire Rehabilitation Scale).
View Article and Find Full Text PDFAcute Hemorrhagic Leukoencephalitis in a Patient With Hepatitis B.
Cureus
August 2024
Cardiology, MGM Healthcare, Chennai, IND.
Article Synopsis
- Acute Hemorrhagic Leukoencephalitis (AHLE) is a rare, fast-progressing brain condition characterized by severe inflammation and hemorrhage, often triggered by infections, with a high mortality rate and significant disability for survivors.
- A case study of a 46-year-old woman with chronic hepatitis B revealed she experienced neurological symptoms, initially misdiagnosed as demyelination, but later confirmed as AHLE after further MRI scans showed hemorrhagic lesions.
- The patient's eventual recovery, despite severe initial symptoms, underscores the importance of early detection and aggressive treatment in improving outcomes for patients with AHLE linked to chronic viral infections.
Long-term persistence of mitochondrial dysfunctions after viral infections and antiviral therapies: A review of mechanisms involved.
J Med Virol
September 2024
Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, Etablissement Français du Sang, University of Antilles, Montpellier, France.
Mitochondria are vital for most cells' functions. Viruses hijack mitochondria machinery for misappropriation of energy supply or to bypass defense mechanisms. Many of these mitochondrial dysfunctions persist after recovery from treated or untreated viral infections, particularly when mitochondrial DNA is permanently damaged.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!