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The study investigated the enhancement of stability and efficacy in the removal of bivalent nickel ions (Ni(II)) by utilizing a cerium metal-organic framework (Ce-MOF) encapsulated within a food-grade algal matrix. This composite material is integrated into a dual-layer hydrogel containing chitosan and carboxymethyl cellulose. The enhancement of structural integrity in the final product can be attributed to the cross-linking process with epichlorohydrin, leading to the development of Ce-MOF-FGA/CMC-CS hydrogel beads.

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To address the shortcomings of traditional actuators, such as large size, high energy consumption, and slow response, this study developed a conductive and responsive artificial muscle, exploring the operational principles and performance enhancement techniques for artificial muscles made from sodium alginate and graphene oxide. Initially, the research outlined a preparation methodology using sodium alginate, graphene oxide, and nanonickel as primary materials. Subsequent adjustments in the nanonickel content optimized critical performance metrics, including output force, lifespan, and deflection displacement.

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Objective: Motivational interviewing (MI) is a client centered counseling approach which aims to promote behavior change by enhancing patient motivation through the exploration and resolution of ambivalence. This type of psychotherapy, initially designed for the treatment of substance use disorders (SUD), is now seen as an effective way to manage chronic physical and psychiatric diseases. Patients with Dual Diagnosis (DD), people who simultaneously have a SUD diagnosis and a mental illness, are a complex group of psychiatric patients who have a particularly low treatment engagement.

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Exploring the immunomodulatory effects of sertraline: Cytokine modulation and signaling pathway dynamics.

J Neuroimmunol

December 2024

Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Biruni University, Istanbul 34010, Turkiye. Electronic address:

This study explores the nuanced immunomodulatory effects of sertraline, which is widely used in the treatment of major depression, obsessive-compulsive disorder, and anxiety in adults and children. Recent investigations have emphasized the intricate interplay between depression and the body's inflammatory response. This has sparked an exploration into the impact of sertraline on the immune system, an area that still awaits comprehensive exploration.

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Article Synopsis
  • Cardiovascular diseases are the leading cause of death globally, with about 20 million deaths in 2021; cardiovascular implants are crucial but face challenges like poor endothelialisation and rapid thrombosis.
  • Simple modifications using silanes can improve biological interactions on implant surfaces without compromising their overall properties.
  • This study found that aminosilane modified surfaces significantly enhance cardiac endothelial cell growth while reducing smooth muscle cell activity, suggesting that tailored surface chemistry can lead to better outcomes for cardiovascular implants.
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