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INTEGRATING RADIOLOGICAL IMAGING TECHNIQUES INTO ANATOMY EDUCATION: MEDICAL TRAINING ENHANCEMANT THROUGH EARLY CT AND MRI TEACHING.
Probl Radiac Med Radiobiol
December 2024
ASST Ovest Milanese, Neuroimaging Unit, Legnano (Milan), Italy, 20025Centro Diagnostico Italiano S.p.A., Department of Diagnostic Imaging and Stereotactic Radiosurgery, Milan, Italy.
Unlabelled: Brain morphology understanding is essential for radiologists, neurologists, and neurosurgeons. Historically, anatomical learning of brain relied on ex vivo specimens. Modern in vivo brain CT and MRI provide spatial, three-dimensional imaging capabilities crucial to help diagnose diseases, plan surgeries, and monitor treatment progress.
View Article and Find Full Text PDFThe history of lobotomy as a neuropsychiatric intervention in Brazil - a case report of a geriatric patient.
Neurocase
December 2024
Psiquiatria Geriátrica, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Lobotomy was a widespread neurosurgical procedure in the first half of the 20th century. It was used as a treatment for various mental disorders. The development of psychosurgeries in Brazil, their indications, effects, consequences, advancements, as well as the social context of the population subjected to it are revised herein.
View Article and Find Full Text PDFTowards a Unified Set of Diagnostic Criteria for Multiple Sclerosis.
Ann Neurol
November 2024
Queen Square Multiple Sclerosis Center, Department of Neuroinflammation, UCL Institute of Neurology, London, UK.
Objective: The 2017 McDonald criteria continued the separation of diagnostic criteria for relapsing-remitting multiple sclerosis (RRMS) and primary progressive MS (PPMS) for historical, rather than biological, reasons. We aimed to explore the feasibility of a single, unified set of diagnostic criteria when applied to patients with suspected PPMS.
Methods: We retrospectively identified patients evaluated for suspected PPMS at 5 European centers.
Treatment-related survival patterns in diffuse intrinsic pontine glioma using a historical cohort: A report from the European Society for Pediatric Oncology DIPG/DMG Registry.
Neurooncol Adv
September 2024
Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
Background: Our aim is to investigate the association of treatment with survival in patients with diffuse intrinsic pontine glioma (DIPG) by examining 6 historical treatment paths.
Methods: We retrospectively analyzed data from 409 patients with radiologically centrally reviewed DIPG, sourced from the German Society of Pediatric Oncology and Hematology HIT-HGG trial database and the SIOPE-DIPG/DMG Registry. Survival outcomes were estimated using the Kaplan-Meier method, and univariable and multivariable Cox proportional hazard models were estimated to study treatment effects.
Short-course hypofractionated proton beam therapy, incorporating F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial.
Lancet Oncol
December 2024
Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Background: Older patients (aged ≥65 years) with glioblastoma have a worse prognosis than younger patients and a median overall survival of 6-9 months. 3,4-Dihydroxy-6-[F]fluoro-L-phenylalanine (F-DOPA) PET sensitively and specifically identifies metabolically active glioblastoma for preferential targeting. Proton beam therapy potentially improves quality of life (QOL) by sparing more healthy brain tissue than photon radiotherapy.
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