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Blastomycosis Awareness: A Crucial Reminder Amidst the Fifth Pneumonia Episode.
Cureus
December 2024
Department of Pathology, Henry Ford Health, Detroit, USA.
Blastomycosis is a rare fungal infection endemic to North America and parts of Africa. It can be challenging to diagnose until it reaches a critical stage. We present a blastomycosis case in Alabama, emphasizing the importance of early recognition and management.
View Article and Find Full Text PDFOverview of Fungi Classified as Risk Group 3 by the Japanese Society for Medical Mycology.
Med Mycol J
December 2024
Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences.
Article Synopsis
- Fungi are classified into four Risk Groups based on their potential to harm humans, with Risk Group 3 indicating significant dangers, including fatalities.
- This review highlights dangerous fungi like Blastomyces dermatitidis and Cladophialophora bantiana, which are known for severe health impacts and high mortality rates due to laboratory-acquired infections.
- Strict biosafety measures are essential in labs handling these fungi due to their associated risks and documented cases of infections and deaths.
Coinfection of Pulmonary Blastomycosis and Tuberculosis in an Immunosuppressed Patient: A Challenging Clinical Case.
Cureus
October 2024
Internal Medicine, General Hospital of the Institute of Social Security and Services for State Workers, Queretaro, MEX.
Fungal and tuberculosis lung infections are considered differential diagnoses due to their clinical and radiological similarities, but they are not mutually exclusive. In rare cases, both entities may manifest in patients with immunosuppression, which is an indicator of high mortality. This is predominantly due to the low level of suspicion, which consequently results in a delay in treatment and thus represents a significant diagnostic challenge.
View Article and Find Full Text PDFPulmonary Blastomycosis in Two Immunocompetent Patients: The Role of Obesity and Vitamin D Deficiency.
Cureus
September 2024
Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
This case report depicts two patients with morbid obesity who presented to the ED with signs and symptoms of community-acquired pneumonia and were treated accordingly. Despite empiric antibiotic therapy, their symptoms did not subside, prompting further evaluation, which revealed pulmonary blastomycosis. Both patients were also found to have severe vitamin D deficiency.
View Article and Find Full Text PDFEpidemiological and clinical features of a large blastomycosis outbreak at a paper mill in Michigan.
Clin Infect Dis
October 2024
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Article Synopsis
- A significant outbreak of blastomycosis, a serious fungal infection, occurred among workers at a paper mill in Delta County, Michigan, affecting 131 patients from December 2022 to July 2023.
- Hospitalization rates were notable, with 12% requiring hospitalization, and factors like diabetes and elevated urine antigen levels were linked to more severe cases.
- This outbreak is the largest recorded in the U.S., highlighting the importance of early diagnosis to avoid unnecessary antibiotic use and improve treatment outcomes.
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