The effects on male rats of single injections of androgens have been shown; this paper considers the responses of the immune and genital systems. The consequences for the progeny, with special reference to their sex and age, of androgenization of the father are considered in a comparative aspect. Deviations have been recorded in physical and sexual development, as well as in the genital system, in the progeny of both sexes. Furthermore, the male progeny is characterized by increased reactivity of the thymus.

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