The "amotivational syndrome" which has been associated with marijuana use has not been examined systematically in relation to marijuana use and mental health. Light and heavy users were solicited by personal contact. They were asked to complete anonymous questionnaires which measured marijuana, alcohol and cocaine use, perceived states during marijuana intoxication, depressive symptoms in the last year, the Orientation to Life Scale and a modified form of the Thematic Apperception Test, from which Need for Achievement, Affiliation and Power were assessed. Several group comparisons were made: Chronic heavy-users (medians: daily use for 6 years) with and without significant symptoms of depression within the last year were compared with Light users (medians: several times per month for 4.5 years) with and without significant symptoms of depression within the last year. Subjects in all groups reported similar ratings of intoxication (being stoned) during marijuana use. No differences were found in alcohol or cocaine use among the comparison groups. Scores on Need for Achievement were significantly lower in heavy users with depressive symptoms when compared with all other groups. No effects were found among groups in measures of the Need for Affiliation and the Need for Power. Both light and heavy users with symptoms of depression had significantly lower scores than those without depressive symptoms, on the overall Orientation to Life questionnaire and on each subscale measuring Meaningfulness, Manageability and Comprehensibility. These data suggest that amotivational symptoms observed in heavy marijuana users in treatment are due to depression.
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Harm Reduct J
January 2025
Department of Psychiatry and Neurosciences, CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Background: Gamma-hydroxybutyrate (GHB) and its precursors gamma-butyrolactone (GBL) and 1,4-butanediol (BD) have become a significant concern due to the increase in their recreational use and the high risks associated with it (e.g., overdose, addiction, life-threatening withdrawal syndromes).
View Article and Find Full Text PDFBiomed Eng Lett
January 2025
Department of Electronic Engineering, Hanyang University, Seoul, 04763 Republic of Korea.
Demand for user authentication in virtual reality (VR) applications is increasing such as in-app payments, password manager, and access to private data. Traditionally, hand controllers have been widely used for the user authentication in VR environment, with which the users can typewrite a password or draw a pre-registered pattern; however, the conventional approaches are generally inconvenient and time-consuming. In this study, we proposed a new user authentication method based on eye-writing patterns identified using electrooculogram (EOG) recorded from four locations around the eyes in contact with the face-pad of a VR headset.
View Article and Find Full Text PDFBMJ Sex Reprod Health
January 2025
Background: Clinical diagnosis of heavy menstrual bleeding (HMB) is dependent on patient report of menstrual product usage of pads and tampons, but it is unknown if newer reusable menstrual products (cup and underwear) are similarly diagnostic.
Methods: We enrolled 20 regularly menstruating individuals with HMB for two menstrual cycles. Participants completed a retrospective baseline Pictorial Blood loss Assessment Chart (PBAC) at the time of enrolment (eligibility PBAC score ≥100) as well as several different measures with each study cycle.
Neurobiol Dis
January 2025
Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE, USA; Department of Pharmacology & Neuroscience, Creighton University, Omaha, NE, USA; College of Medicine, University of Nebraska Medical Center (UNMC), Omaha, NE, USA. Electronic address:
The legalization of recreational cannabis use has expanded the availability of this psychoactive substance in the United States. Research has shown that chronic cannabis use is associated with altered working memory function, however, the brain areas and neural dynamics underlying these affects remain poorly understood. In this study, we leveraged magnetoencephalography (MEG) to investigate neurophysiological activity in 45 participants (22 heavy cannabis users) during a numerical WM task, whereby participants were asked to either maintain or manipulate (i.
View Article and Find Full Text PDFFood Chem Toxicol
December 2024
Department of Otolaryngology-Head and Neck Surgery, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA; Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA; TSET Health Promotion Research Center, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA. Electronic address:
Electronic cigarettes (e-cigarettes) have emerged as a potential alternative to traditional smoking and may aid in tobacco harm reduction and smoking cessation. E-cigarette use has notably increased, especially among young non-tobacco users, raising concerns due to the unknown long-term health effects. The oral cavity is the first and one of the most crucial anatomical sites for the deposition of e-cigarette aerosols.
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